Late-onset Treatment Resistant Isolated Oromandibular Dystonia: A case report
Objective: We hereby report a case of oromandibular dystonia with onset in late 70s and symptoms resistant to symptomatic therapy including onabotulinum toxin A. Background:…The effects of acute administration of VMAT2 inhibitors on extracellular levels of dopamine, norepinephrine, 5-HT and histamine in the striatum and medial prefrontal cortex
Objective: To evaluate the effects of reversible VMAT2 inhibitors (deutetrabenazine, tetrabenazine and valbenazine) on extracellular levels of monoamines and their acidic metabolites in rat striatum…Cumulative Real-World Experience with Deutetrabenazine for Huntington’s Disease Chorea at a Single Center of Excellence in the US
Objective: To summarize clinical experience and outcomes with deutetrabenazine (DTBZ) as a treatment for Huntington’s disease (HD) chorea from the Huntington’s Disease Society of America…Evaluation of the QTc prolongation risk of deutetrabenazine
Objective: To assess QTc prolongation risk of deutetrabenazine and its active metabolites by conducting exposure-QTc interval modeling, and to predict QTc prolongation in both CYP2D6…Deutetrabenazine for Huntington’s disease chorea—A Single Center’s Experience
Objective: To evaluate real-world use and outcomes with deutetrabenazine for Huntington’s disease. Background: Grade A evidence for Huntington’s disease chorea treatment includes tetrabenazine and deutetrabenazine.…Generalized chorea in a patient with isolated leukocytosis and JAK2V617F mutation: A case report
Objective: To describe late-onset generalized chorea in a patient found to have the JAK2V617F mutation without polycythemia vera. Background: Polycythemia vera (PV) is well-known to…Comparing risperidone and olanzapine to tetrabenazine for the management of Huntington’s chorea
Objective: To compare the efficacy of risperidone and olanzapine to tetrabenazine (TBZ) for the management of Huntington’s chorea in Enroll-HD participants. Background: TBZ is provenly-effective…Demographic and Clinical Characteristics and Tetrabenazine (TBZ) Persistence in Patients With Huntington Disease (HD)-Associated Chorea
Objective: To characterize demographic and clinical characteristics of HD patients with chorea based on TBZ use status, and to examine treatment persistence with TBZ in…A Descriptive Analysis of a Real-World Population With Huntington Disease-Associated Chorea (HDAC) Treated With Tetrabenazine: Findings From an Electronic Medical Records (EMR) Database
Objective: To examine clinical and treatment information about HDAC in patients (pts) prescribed tetrabenazine (TBZ). Background: Huntington disease is a hereditary movement disorder, with chorea…Probable REM sleep behaviour disorder and detrusor overactivity in primary cervical dystonia- A case report
Objective: To report two atypical associations of pRBD and DO we came across with a case of primary cervical dystonia. Background: RBD (REM sleep Behaviour…