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Early integrated Dysphagia and Nutritional Management in Parkinsonism: a prospective Feasibility Study to prevent Malnutrition and Complications

Y. Zashchypas, S. Lorenzl (SAlzburg, Austria)

Meeting: 2026 International Congress

Keywords: Dysphagia, Interventions, Parkinson’s

Category: Parkinson's Disease: Non-Motor Symptoms (non-Cognitive/ non-Psychiatric)

Objective: To assess feasibility, safety, adherence, and acceptability of an early integrated dysphagia–nutrition pathway for parkinsonism.

Background: Dysphagia in parkinsonism may occur early and remain under-recognized, contributing to weight loss, dehydration, and respiratory morbidity. Pragmatic pathways that translate swallowing diagnostics into timely nutritional action and structured monitoring are not routinely implemented.

Method: Adults with parkinsonism and dysphagia risk (Eating Assessment Tool-10), clinician concern, or unintentional weight loss will receive standardized bedside assessment (GUSS) and/or (MASA) and FOIS grading. FEES and/or VFSS will be performed after bedside triage for: recurrent aspiration pneumonia in the medical history; clinical suspicion of silent aspiration at bedside; and/or clinically significant, rapid unintentional weight loss (≥5% within 1 month or ≥10% within 6 months), indicative of inadequate oral intake potentially attributable to swallowing impairment. Instrumental findings will be quantified with scales (PAS, MSS, YPRSRS). Nutrition evaluation will include body mass index, weight-change %, and Nutrition Risk Screening (NRS-2002) or Mini Nutritional Assessment (MNA) to set individualized energy/protein targets. Dysphagia diet planning (food texture and fluid consistency modification) will follow the International Dysphagia Diet Standardisation Initiative (IDDSI). A diary will track intake, hydration, and weekly weight; swallowing findings will guide texture/fluid recommendations and nutrition-support actions. We plan to enroll 50 patients with Parkinson’s Disease.

Results: Primary outcomes will be feasibility/implementation metrics (recruitment, retention, completion rates, time-to-completion, diary adherence, acceptability). Secondary outcomes will describe within-participant change in nutritional status, oral intake (FOIS), instrumental safety/efficiency (PAS/MSS/YPRSRS), and dysphagia-related complications during follow-up. Preliminary data will be presented at the congress.

Conclusion: This diagnose-to-nutrition pathway integrates bedside triage with FEES/VFSS as needed and operationalizes early nutritional support in parkinsonism. Feasibility results will guide pathway refinement and a subsequent effectiveness study.

References: 1. Andre C, et al. ESPEN guideline on clinical nutrition in neurology. Clin Nutr. 2023;42(2):399–452.
2. Barichella M, Cereda E, Pezzoli G. Major nutritional issues in Parkinson’s disease. Mov Disord. 2009;24(13):1881–1892.
3.Clave P, Shaker R. Dysphagia: current diagnostic and therapeutic approaches. J Am Geriatr Soc. 2021;69(7):1783–1790.
4.Dilmaghani S, Atieh J, Khanna L, Hosfield EA, Camilleri M, Katzka DA. Oropharyngeal dysphagia: mechanisms, evaluation and management. Clin Gastroenterol Hepatol. 2023;21(6):1570–1583.
5.Serra-Prat M, Palomera E, Gomez C, et al. Oropharyngeal dysphagia as a risk factor for malnutrition and mortality. Age Ageing. 2012;41(3):376–381.
6. Stavroulakis T, Baird WO, Baxter S, et al. Gastrostomy in ALS: timing, indications and impact on survival. J Neurol. 2016;263(4):839–847.

To cite this abstract in AMA style:

Y. Zashchypas, S. Lorenzl. Early integrated Dysphagia and Nutritional Management in Parkinsonism: a prospective Feasibility Study to prevent Malnutrition and Complications [abstract]. Mov Disord. 2026; 41 (suppl 1). https://www.mdsabstracts.org/abstract/early-integrated-dysphagia-and-nutritional-management-in-parkinsonism-a-prospective-feasibility-study-to-prevent-malnutrition-and-complications/. Accessed October 1, 2026.
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