Objective: To investigate the effect of poor sleep quality on fatigue severity
Background: Poor sleep quality is observed in 60% of Parkinson’s Disease (PD). The incidence of fatigue varies between 36-60%. The relationship between these two common non-motor symptoms is controversial. Some studies suggest that sleep disturbance, is an independent predictor of fatigue, while others show a moderate relationship between them. Some studies claim that fatigue in PD may be related to anxiety, but not to sleep disorder. One study showed poor sleep quality is associated with fatigue and depression, not with disease severity
Method: Fifty-two PD patients (26 women, 26 men) participated in the study. Patients were administered the UPDRS part III, The Pittsburgh Sleep Quality Index (PSQI), Fatigue Severity Scale, Beck Depression Questionnaire, Beck Anxiety Questionnaire. The total score of the PSQI, its subgroups (part 2 for sleep latency, part 3 for sleep duration) were calculated. The total score of the Fatigue Severity Scale, item 8 (fatigue is among my three most disabling symptoms), and item 9 (fatigue interferes with my work, family, or social life) were also determined. The effect of sleep quality on fatigue were investigated
Results: The mean age of the patients was 59.60±12.69, the duration of the disease was 8.54±4.68 years. The mean levodopa dose was 921.39±612.69 mg. Patients with lower sleep quality had higher total levodopa doses, longer disease duration, higher total fatigue, depression and anxiety scores, and a greater impact on daytime disability. Patients with longer sleep latency had higher fatigue, depression and anxiety scores.
Conclusion: In our study, we found that those with poor sleep quality were more likely to have advanced disease and disability, experienced more severe fatigue and had psychological problems. Considering that poor sleep quality and fatigue can be affected by many factors, further studies with more patients and non-motor parameters are needed in this field.
To cite this abstract in AMA style:
N. Helvacı Yılmaz, ö. Köksal, G. İbrahimova, B. Arı, İ. Emekli, G. Yılmaz çakan, M. Samancı, T. Zırh, G. Kenangil. Effect of Poor Sleep Quality on Fatigue Severity in Parkinson’s Disease [abstract]. Mov Disord. 2026; 41 (suppl 1). https://www.mdsabstracts.org/abstract/effect-of-poor-sleep-quality-on-fatigue-severity-in-parkinsons-disease/. Accessed October 1, 2026.« Back to 2026 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/effect-of-poor-sleep-quality-on-fatigue-severity-in-parkinsons-disease/