Objective: To assess the prevalence and patterns of neuropsychiatric symptoms among patients with Parkinson’s disease in low- and middle-income countries (LMICs).

Background: Neuropsychiatric manifestations such as depression, anxiety and cognitive impairment significantly contribute to disability and reduced quality of life in patients with PD. Data from LMICs remain limited.

Method: A systematic search of PubMed, Embase and Scopus was conducted to identify studies reporting neuropsychiatric symptoms among PD patients in LMICs. Studies were screened and relevant prevalence data were extracted.

Results: Seventeen studies from 11 LMICs met the inclusion criteria. Depression prevalence ranged from 32% to 58%, anxiety from 28% to 52%, and cognitive impairment was reported in up to 40% of patients. Limited access to psychiatric services and delayed diagnosis were common across the included studies.

Conclusion: Neuropsychiatric symptoms are highly prevalent among PD patients in LMICs but remain underrecognized and undertreated. Integrating mental health screening into PD management may improve patient outcomes in resource-limited settings.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/neuropsychiatric-symptoms-in-parkinsons-disease-in-low-and-middle-income-countries-a-systematic-review/