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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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2025 International Congress » MSA, PSP, CBS: Disease Mechanisms

Meeting: 2025 International Congress

A rapidly progressive multiple system atrophy-cerebellar variant model presentingα-synuclein oligomer spreading and phosphorylated α-synuclein aggregate formation accompanied with glial inflammation

D. Matsuse, H. Yamaguchi, Y. Nishimura, H. Sekiya, K. Masaki, T. Tanaka, T. Saiga, M. Harada, K. Kira, D. Dickson, K. Fujishima, E. Matsuo, K. Tanaka, R. Yamasaki, N. Isobe, J. Kira (Fukuoka, Japan)

Atrophy In Multiple System Atrophy Relates To Mitochondrial And Oligodendrocytic Processes

L. Chougar, C. Tremblay, A. Delva, M. Filiatraul, A. Vo, J. Hansen, A. Farahani, B. Misic, P. Khalafi, CE. Castonguay, G. Rouleau, JC. Corvol, M. Vidailhet, B. Degos, D. Grabli, S. Lehéricy, A. Dagher, S. Rahayel (Montreal, Canada)

Neuroinflammatory response is determined by HLA genotype in progressive supranuclear palsy

G. Kovacs, H. Chasiotis, S. Zaheer, J. Wang, J. Li, MC. Tartaglia, S. Fox, A. Lang, S. Forrest (Toronto, Canada)

Novel Heterozygous Variant in DCTN1 Associated with Perry Syndrome

D. Yang, Y. Zhang, Z. Cen, W. Luo (Hangzhou, China)

Quantitative Regional Tau Pathology and Spatial Transcriptomics Identify Signatures of Phenotypic Diversity in Progressive Supranuclear Palsy.

P. Cullinane, J. Parmera, T. Curless, L. Paras Chajed, S. Wrigley, W. Sifontes Valladares, J. Anton Arnal, M. Burrows, K. Ebanks, M. Blunskyte, D. Gavriouchkina, L. Binding, T. Revesz, S. Brandner, A. Young, E. de Pablo-Fernández, H. Morris, Y. Lim, H. Nelvagal, T. Warner, Z. Jaunmuktane (London, United Kingdom)

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