Objective: The objective of NS-PARK/FCRIN network (http://www.parkinson.network/) is to facilitate and stimulate clinical academic and industrial research in France in the field of Parkinson’s disease (PD) and movement disorders. NS-PARK is primarily focused in two types of projects: (i) Early translational and “Proof of Concept” studies, for testing new pharmacological or non-pharmacological therapeutic targets; (ii) Large national/international multicenter trials for evaluating new treatments, therapeutic strategies or to reposition existing treatments.

Background: The NS-PARK/FCRIN network is a national clinical research network bringing together the main researchers and clinical experts in the field in France. NS-PARK is chaired by Prof. Rascol (Toulouse), Prof. Corvol (Paris, Pitié Salpêtrière) and Prof. Durif (Clermont-Ferrand) and includes the 24 French expert centers for PD designated by the French Ministry of Health. The French Deep Brain stimulation network and the French PD genetics network (PDG network) joined NS-PARK strengthening their visibility and allowing a global approach of PD. Moreover, NS-PARK has numerous collaborations with preclinical research teams and patients’ associations.

Methods: NS-PARK gathers a scientific and methodological expertise (key opinion leaders at the national and international levels, access to all French PD experts centers, long experience of partnerships with pharmaceutical companies, relationship with French research institutes for Neurosciences) and an efficient operational organization with a common national registry of PD patients (> 15 000 patients) allowing a global vision of the active file of patients followed up in the experts centers, a standardized and harmonized costs grid across centers, recruitment strategies before and during the trials, a common quality system, an access to clinical research facilities such as neuroimaging or biobanking. Two project managers are dedicated to NS-PARK activities.

Results: Since 2010, NS-PARK has been involved in more than 50 academic and industrial trials on PD and movement disorders (47% were industrial studies) and in nearly 50 publications in international peer-reviewed journals.

Conclusions: NS-PARK/FCRIN network is an efficient structure to promote, facilitate and implement translational and clinical research in the field of PD and movement disorders.

« Back to 2017 International Congress

MDS Abstracts - https://www.mdsabstracts.org/abstract/ns-parkfcrin-network-the-french-clinical-research-network-for-parkinsons-disease-and-movement-disorders/