Objective: To demonstrate a successful treatment of neuroleptic-induced generalized dystonia with DBS

Background: Male patient, 30 years old.
At thirteen years of age, was diagnosed with DiGeorge Syndrome and developed severe anxiety disorder. Was referred to a psychiatrist and treat with quetiapine and risperidone intermittently. In 2017 was prescribed Haloperidol and Lithium. After that, developed generalized dystonia, mainly cervical, truncal and upper right limb. Evolved with progressive limitations to daily living activity. In 2018, medication withdrawal and botulin toxin injections were unsuccessful in reverting the symptoms.  In May 2018, was referred to the Movement Disorders Department at Neurological Institute of Curitiba, where after evaluation from the neurological e neurosurgical specialists, was submitted to bilateral GPi-DBS. After 6 months of adjustments, has had marked improvement of dystonic symptoms, having gone back to school and become independent for daily living activities. Currently, id using Valproic Acid 750mg/daily.

Method: Non-applicable due to being a case-report

Results: With videos to suport, patient has gone from being bed-ridden to independent walk.

Conclusion: Tardive Dystonia can be a limiting condition and, similarly to idiopathic dystonia, can be successfully treated with GPi-DBS.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/tardive-dystonia-successfully-treated-with-dbs/