Levodopa-Responsive Dystonia in Adenylosuccinate Lyase (ADSL) Deficiency Treated With Bilateral GPi Deep Brain Stimulation
Objective: To describe levodopa-responsive dystonia in ADSL deficiency and the use of bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) for refractory symptoms. Background:…Risk of Ischemic Cerebrovascular Events in Patients with Deep Brain Stimulation for Parkinson’s Disease: A Cohort Study
Objective: To longitudinally assess the risk of ischemic cerebrovascular events in patients undergoing DBS Background: Longitudinal data on the potential impact of DBS on long-term…A Case Report: Optimising Motor and Non-Motor Control in Advanced Parkinson’s Disease: The Role of Foslevodopa/Foscarbidopa After Deep Brain Stimulation
Objective: To investigate the combined use of continuous subcutaneous foslevodopa/foscarbidopa and deep-brain stimulation in managing advanced Parkinsons Disease. Background: Continuous foslevodopa/foscarbidopa subcutaneous (SC) infusion has been shown…Stimulation-Level Sweet-Spot and Connectivity Analysis of Pallidal DBS in Huntington’s Disease
Objective: To assess clinical outcomes and identify stimulation and structural connectivity patterns associated with motor improvement in Huntington’s Disease (HD) patients undergoing DBS. Background: DBS…Two-year Outcomes of Rapid Eye Movement Behavior Disorder Following Globus Pallidus Interna Deep Brain Stimulation for Parkinson’s Disease
Objective: This study evaluated two-year outcomes of rapid eye movement (REM) sleep behavior disorder (RBD) in a cohort of patients with Parkinson’s disease (PD) who…Globus Pallidus Internus Deep Brain Stimulation for Dystonia in COX20-Related Mitochondrial Complex IV Deficiency (MC4DN11): First Reported Case
Objective: To describe the clinical response to bilateral GPi-DBS in a patient with MC4DN11-associated dystonia. Background: Mitochondrial Complex IV Deficiency, Nuclear Type 11 (MC4DN11), caused…Data Driven Clinical Insights from Longitudinal Cloud-Aggregated Neural Data to Inform a Real-World Adaptive DBS Programming
Objective: Characterize clinical workflow insights gained from expanded access to neural data via a cloud connected platform in adaptive DBS. Background: Adaptive deep brain stimulation…Automated Image-guided Programming for DBS Matches Expert Clinician Programming
Objective: To compare Volumes of Tissue Activated (VTA) locations and motor outcomes in Parkinson’s Disease (PD) patients across three programming strategies: manual image-guided programming (mIGP),…Life Changing Diagnoses; Distinguishing Holmes Tremor from Functional Tremor
Objective: - Background: Holmes tremor is a rare etiology defined as a unilateral, irregular, <4.5 Hz rest and intention tremor which typically presents 4 weeks to 2 years from occurrence…Deep brain stimulation effects on Parkinson’s disease patients with orthostatic hypotension
Objective: To evaluate orthostatic blood pressure changes before and after subthalamic deep brain stimulation (STN-DBS) and to determine whether outcomes were related to DBS therapy…
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