Category: Other
Objective: To Evaluate the therapeutic and preventive effect of OnabotulinumtoxinA in the treatment of trigeminal neuralgia (TN) and chronic migraine (CM) in patients with bilateral hemifacial spasm (BHF).
Background: OnabotulinumtoxinA (BoNT/A) is effective to treat several movement disorders. Recent studies have suggested that BoNT/A is effective in pain syndromes.
Method: We conducted an open administration of OnabotulinumtoxinA in 4 patients with BHF, TN and CM. Patients reported medication use before and after intervention BoNT/A injections at 30, 90, 180 and 270 days. Improvement in hemifacial spasm, pain and ADLs were evaluated.
Results: All patients with trigeminal neuralgia, chronic migraine and impairment in activities of daily living had a substantial improvement in hemifacial spasm and pain reduction after OnabotulinumtoxinA (Table 1) (Table 2).
Conclusion: OnabotulinumtoxinA is effective in the treatment of an unusual combination of hemifacial spasm, trigeminal neuralgia and chronic migraine, improving hemifacial spasm and reducing pain in TN and CM.
To cite this abstract in AMA style:
J. Lopez-Castellanos, J. Lopez Contreras. Therapeutic effect of OnabotulinumtoxinA in bilateral hemifacial spasm, trigeminal neuralgia and chronic migraine in El Salvador [abstract]. Mov Disord. 2020; 35 (suppl 1). https://www.mdsabstracts.org/abstract/therapeutic-effect-of-onabotulinumtoxina-in-bilateral-hemifacial-spasm-trigeminal-neuralgia-and-chronic-migraine-in-el-salvador/. Accessed June 15, 2025.« Back to MDS Virtual Congress 2020
MDS Abstracts - https://www.mdsabstracts.org/abstract/therapeutic-effect-of-onabotulinumtoxina-in-bilateral-hemifacial-spasm-trigeminal-neuralgia-and-chronic-migraine-in-el-salvador/