Category: Parkinson's Disease (Other)
Objective: To highlight a complex clinical case of coexisting movement and neuromuscular junction (NMJ) disorders.
Background: Essential tremor (ET) is the most common movement disorder worldwide. Approximately 3-5% of patients with ET may later develop Parkinson’s disease (PD). In contrast, Myasthenia Gravis is a relatively rare (NMJ) disorder characterized by a bimodal age distribution.
Method: case report
Results: We present an 83-year-old patient with longstanding action and postural tremors, initially diagnosed as essential tremors. Over time, the patient developed bradykinesia and rigidity, meeting the clinical criteria for PD, with symptomatic improvement following levodopa therapy. At the age of 82, the patient developed fatigable diplopia. Further evaluation revealed positive acetylcholine receptor (AChR) antibodies, and the patient experienced clinical improvement on pyridostigmine and corticosteroid therapy.
Conclusion: We highlighted a rare and diagnostically challenging case involving essential tremor and Parkinson’s disease with late development of Myasthenia Gravis.
To cite this abstract in AMA style:
I. Eltazi, B. Canibano, O. Suliman. Perplexing Presentation of Myasthenia Gravis in an Elderly Patient with Essential Tremor and Parkinson’s Disease Complex Case Report [abstract]. Mov Disord. 2026; 41 (suppl 1). https://www.mdsabstracts.org/abstract/perplexing-presentation-of-myasthenia-gravis-in-an-elderly-patient-with-essential-tremor-and-parkinsons-disease-complex-case-report/. Accessed October 1, 2026.« Back to 2026 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/perplexing-presentation-of-myasthenia-gravis-in-an-elderly-patient-with-essential-tremor-and-parkinsons-disease-complex-case-report/