Objective: The objective of the study was to assess the psychotic symptoms associated with Parkinson’s disease (PD) and to establish statistical correlations with sociodemographic and clinical characteristics of PD.
Background: Parkinson’s disease (PD) is recognized for both its motor and non-motor symptoms. While there are a variety of non-motor symptoms, psychiatric disturbances remain often overlooked despite their common occurrence and significant impact on daily functioning.
Method: We conducted a transversal population-based study of patients followed in the department of Neurology of Charles Nicolle hospital of Tunisia for PD.
We were able to specify psychotic disorders using a semi-structured interview based on DSM-IV. Statistical analysis was performed using SPSS version 18.
Results: Our study included 30 patients with PD. The average age of our patients was 64.17+-9 years with a sex ratio of 0.66.
A revealing psychiatric clinical picture was observed in 36.7% of patients.
Psychotic signs were reported by 43.3% patients. Hallucinations were found in 33.3%. They were predominantly visual=90% associated with auditory=40% and tactile=10%.
Delusion was noted in 10%, divided into ideas of persecution=60%, references=20% and jealousy=20%. In fact, Fénelon and al reported that the frequency of delirium varies from 1 to 14%. In our study, psychotic symptoms and patients sociodemographic characteristics, age of disease onset and L-dopa daily dose, were statistically independent.
Conclusion: Our study analyzed meticulously the various aspects of psychotic disorders in PD. As perspectives, further antipsychotic trials in patients with psychosis in PD are required.
To cite this abstract in AMA style:
S. Frikha, O. Ben Othmen, M. Ben Mahmoud, S. Fray, H. Jamoussi, M. Fredj, N. Ben Ali. Psychotic features in patients with Parkinson’s disease [abstract]. Mov Disord. 2024; 39 (suppl 1). https://www.mdsabstracts.org/abstract/psychotic-features-in-patients-with-parkinsons-disease/. Accessed October 7, 2024.« Back to 2024 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/psychotic-features-in-patients-with-parkinsons-disease/