Session Time: 1:45pm-3:15pm
Location: Hall 3FG
Objective: We aimed to assess the relationship between EEG abnormalities and MTLA, and its clinical validity in Parkinson’s disease with behavioral and psychological symptoms.
Background: Behavioral and psychological symptoms in dementia are often seen in patients with Parkinson’s disease. The electroencephalogram (EEG) abnormalities in dementia have been widely reported and medial temporal lobe atrophy (MTLA) is one of the hallmarks in early stage of dementia.
Methods: A total of 20 Parkinson’s disease patients with behavioral and psychological symptoms were recruited (the mean age: 71.83 years). Baseline EEGs were analyzed with quantitative spectral analysis. MTLA was assessed by a T1-axial visual rating scale.
Results: In relative power spectrum analysis according to the right MTLA severity, the power of theta waves in C4, T4, F4, F8, and T5 increased significantly and the power of beta waves in T6, C4, T4, F8, T5, P3, T3! , F7 decreased significantly in severe atrophy group. In relative power spectrum analysis according to the left MTLA severity, the power of theta waves in T3 increased significantly and that of beta waves in P4, T6, C4, F4, F8, T5, P3, C3, T3, F3, F7 decreased significantly in severe atrophy group.
Conclusions: The severe MTLA group, regardless of laterality, showed more severe quantitative EEG alterations. These results suggest that quantitative EEG abnormalities are correlated with the MTLA, which may play a important role in Parkinson’s disease patients with behavioral and psychological symptoms.
To cite this abstract in AMA style:J.Y. Ahn, H.T. Kim. Quantitative EEG and medial temporal lobe atrophy in early Parkinson’s disease with behavioral and psychological symptoms [abstract]. Mov Disord. 2018; 33 (suppl 2). https://www.mdsabstracts.org/abstract/quantitative-eeg-and-medial-temporal-lobe-atrophy-in-early-parkinsons-disease-with-behavioral-and-psychological-symptoms/. Accessed December 11, 2023.
« Back to 2018 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/quantitative-eeg-and-medial-temporal-lobe-atrophy-in-early-parkinsons-disease-with-behavioral-and-psychological-symptoms/