Category: Parkinson’s Disease: Clinical Trials
Objective: The present study prospectively tested the effects of the subjective postural vertical on the exacerbation of the forward flexion of trunk (FFT) through long-term observation of Parkinson’s disease subjects.
Background: We developed a novel method to measure the angle of subjective postural vertical (SPV) and showed that the SPV may be related to the exacerbation of the forward flexed posture.
Method: Evaluation of the posture included measuring FFT, the angle of lateral flexion of trunk, and the angle at the position that the subject subjectively perceived as the vertical position at a stationary upright position immediately after standing up at the time of initial observation, 6 months later, and 1 year later.
Results: The SPV angles worsened significantly at 6 months and 1 year compared to the first measurements, such as 9.3 ± 6.7° vs. 10.8 ± 8.2°, 10.6 ± 7.8°, and P < 0.05, and the FFT angles worsened significantly at one year compared to the first measurements, such as 11.1 ± 8.1° vs. 12.2 ± 8.8°, P = 0.004. Additionally, the magnitude of change in the FFT angles was significantly higher in the group with a SPV ratio (SPV/FFT) of 1 or greater than the group with the SPV ratio of less than 1 (P = 0.014).
Conclusion: For the first time, a longitudinal study of a large number of cases showed that the SPV and the FFT change in tandem. Thus, the change in the SPV may precede the change in the FFT.
To cite this abstract in AMA style:
M. Shiraishi, K. Mikami, H. Kamo, Y. Okuma, T. Tsunemi, K. Fujimoto, T. Kamo, Y. Yokota, S. Nogawa, T. Osada, M. Seki, H. Nagayama, T. Hatano, H. Nakajima, K. Suzuki, T. Yamamoto, Y. Yamano, N. Hattori, M. Ijima. The Effect of Subjective Postural Vertical on Forward Flexed Posture in Parkinson’s disease [abstract]. Mov Disord. 2024; 39 (suppl 1). https://www.mdsabstracts.org/abstract/the-effect-of-subjective-postural-vertical-on-forward-flexed-posture-in-parkinsons-disease/. Accessed October 6, 2024.« Back to 2024 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/the-effect-of-subjective-postural-vertical-on-forward-flexed-posture-in-parkinsons-disease/