Neuroanatomical correlates of depressive symptoms in newly diagnosed Parkinson’s disease patients
Objective: Depression is the most frequent neuropsychiatric manifestation in Parkinson's disease (PD). Although evidence suggests that depression in PD is related to the degenerative process…Central Aortic Pressure in Parkinson’s Disease and Levodopa Effect
Objective: Central aortic pressure (CAP) is the systolic blood pressure at the root of the aorta. In young people CAP is lower than the peripheral…Pain and Parkinson’s disease
Objective: We aimed to explore clinical correlates and risk factors in the development of pain, alongside the relationship between pain and striatal dopaminergic dysfunction in…Non-motor symptoms in Parkinsons’s disease patients treated with levodopa-carbidopa intestinal gel infusion- the follow up study
Objective: To follow up the effect of continuous levodopa-carbidopa intestinal gel infusion (LCIG) on motor and non-motor symptoms in advanced Parkinson’s disease (aPD). Background: Non-motor…Association of pain and depression with Parkinson’s disease-osteoarthritis comorbidity.
Objective: The goal of this study was to observe if additional pain associated with comorbid symptomatic OA in PD patients is correlated with greater depression…Cognitive Impairment in MSA Patients from the Catalan Multiple System Atrophy Registry (CMSAR)
Objective: To assess the cognitive function and its demographic and clinical correlates in MSA patients included in the Catalan Multiple System Atrophy-Registry (CMSAR). Background: Cognitive…Impulse control disorders in Parkinson’s disease; description of a New Zealand cohort
Objective: Impulse control disorders (ICDS) are a recognised complication of dopaminergic therapy for Parkinson’s disease. We wanted to assess the rates of ICDs in New…Differential microRNA expression in a cohort of Parkinson’s disease patients
Objective: To develop a blood test that will use micro RNA (miRNA) to identify patients with PD Background: PD is a progressive neurodegenerative disorder and…Parkinsonism through astrocytic GABA induce motor symptoms
Objective: Although reactive gliosis is a prominent feature of PD, its role in pathogenesis has remained elusive. Here we show that aberrantly synthesized GABA from reactive astrocytes tonically inhibits neighboring dopaminergic neuronal firing in SNpc, reducing dopamine production and release, leading to parkinsonian motor symptoms. Background: Parkinsonism is a clinical syndrome of movement abnormalities seen in Parkinson’s disease (PD), which has been attributed to cell-autonomous mechanism of doparminergic neuronal death in the substantia nigra pars compacta (SNpc). Methods: To identify the…Progressive Supranuclear Palsy : About one case at the Neurology Department – Dakar
Objective: We report an observation of a case received at the consultation in the Neurology Department of National Teaching Hospital Fann. Background: Progressive supranuclear palsy…
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