Neuroprotective potential of curcumin in combination with piperine against 6-hydroxy dopamine induced motor deficit and neurochemical alterations in rats
Objective: (1) Curcumin is well tolerated curcuminoid used as supplement for various disorders but problem is its low oral bioavailability. (2) Piperine is combined to…Cognitive Impairment and Depression in Patients with Parkinson’s Disease
Objective: To evaluate cognitive impairment and depression in patients with Parkinson's Disease (PD) and its relationship. Background: Patients with Parkinson's disease are prone to cognitive…Distinct networks contribute to the dysexecutive and posterior cortical cognitive syndromes of cognitive impairment in Parkinson’s Disease
Objective: The objective of the current study is to relate the network degeneration and the dual syndrome hypothesis of cognitive impairment in Parkinson’s Disease (PD).…Integrated whole exome sequencing and chromosomal microarray in familial Parkinson’s disease
Objective: To determine whether whole exome sequencing (WES) plus chromosomal microarray analysis (CMA) yield a genetic etiology in a cohort of 110 individuals with familial…Nucleotide repeats as genetic risk factors in a Swedish Parkinson’s disease cohort
Objective: To search for abnormal NRE in the following genes: ATXN2, ATXN3, CACNA1A, TBP, c9orf72, PRNP, POLG1A and TOMM40 in a Swedish PD cohort. Background:…Downregulation of blood serum microRNA 29 family in patients with Parkinson’s disease
Objective: The aims of the present study were to profile the expression of microRNA29 family (miR-29s) in blood serum from patients with PD vs unaffected…Association of GBA polymorphisms and mutations with dementia in Parkinson disease: A 7-year study of three population-based incident cohorts
Objective: To study the effect of GBA variants on dementia in three deeply phenotyped population-based prospective cohorts of patients with incident Parkinson disease. Background: Dementia…Molecular mechanisms of GCH1-associated Parkinson’s disease
Objective: To unravel the molecular mechanisms by which loss of GCH1 function enhances the risk of Parkinson´s disease (PD). Background: Loss-of-function mutations in GCH1 are…Exploring novel diffusion-derived biomarkers in Parkinson’s disease Freezing of Gait
Objective: To explore the association between novel diffusion-derived structural imaging biomarkers and disease duration in Parkinson’s disease with freezing of gait (PD-FOG). Background: Increasing free-water…STN DBS modulates cortical auditory processing in advanced Parkinson’s Disease; a MEG-study
Objective: To find out how deep brain stimulation (DBS) impacts cortical auditory processing in advanced Parkinson's disease (PD) patients. Background: Motor symptoms of PD can…
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