A new SPG4/SPAST mutation in an Italian family with hereditary spastic paraplegia and Alzheimer’s disease
Objective: To perform a clinical and a genetic study in an Italian family with a complicated form of hereditary spastic paraplegia (HSP) and Alzheimer’s disease…Perry syndrome: Proposal of international diagnostic criteria and a new disease concept
Objective: To propose international diagnostic criteria for Perry syndrome and a new disease concept. Background: Perry syndrome is a rare autosomal dominant neurodegenerative disease characterised…Striatal dopamine function in multiple system atrophy and progressive supranuclear palsy: A meta-analysis of imaging studies
Objective: To investigate differences in striatal presynaptic dopamine function between multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) using combined data from all available…Cognition related to striatal dopaminergic function in healthy subjects, in consideration to aging
Objective: The aim of the present study was to find the relationship between striatal dopamine transporter (DAT) and cognitive function in healthy subjects and these…Ginsenoside Rb1 protects dopaminergic neurons through Foxm1-Nurr1 pathway in mice model of Parkinson’s disease
Objective: In the present work, we investigated the protective effects of ginsenoside Rb1 in dopaminergic neurons through Foxm1-Nurr1 pathway in mice model of Parkinson’s disease.…Cortical myoclonus explained by cerebellar dysfunction: Evidence from a unique case
Objective: To give a thorough neurophysiological description of a patient presenting with unilateral cortical myoclonus and homolateral congenital cerebellar hemiatrophy Background: The role of the…Effect of finger rhythmic movement training on freezing of gait in Parkinson’s disease patients: A study protocol
Objective: To investigate the effect of finger rhythmic movement (FRM) training on freezing of gait (FOG) in Parkinson's disease (PD) patients. Background: External cues such…Effects of the Lee Silverman Voice Treatment (LSVT LOUD ®) on Facial Expressivity in Individuals with Parkinson’s Disease (PD) as a function of Emotional Valence
Objective: To examine the effect of LSVT LOUD (Ramig et al., 2011) on facial expressivity in PD as a function of emotional valence. Background: Research…The anti-dyskinetic effect of the clinically-available 5-HT3 receptor antagonist granisetron in the 6-OHDA-lesioned rat model of Parkinson’s disease
Objective: To determine the effect of the serotonin 3 (5-HT3) receptor antagonist granisetron, a clinically-available anti-emetic, on L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesia. Background: Dopamine replacement with L-DOPA…Relationship between Patient Global Impression of Change and other Efficacy Endpoints in Parkinson’s Disease: A post-hoc analysis from combined BIPARK-I and II
Objective: To evaluate the association of patients’ perception of Parkinson’s Disease (PD) symptoms improvement (as assessed by Patient Global Impression of Change, PGIC) could be…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.