Low body weight is associated with poor functional status in Parkinson’s disease (PD)
Objective: To assess if low body weight and malnutrition is associated with poor functional status in PD. Background: It has been observed that many advanced…Apathy in Parkinson’s disease is associated with abnormal alpha oscillatory behaviour during incentivized movement
Objective: To determine the relation between apathy and neural oscillations in Parkinson’s disease (PD). Background: Apathy in PD, characterized by lack of motivation, is often…Multisite Tissue and Biofluid Sampling for Alpha-Synuclein in Parkinson’s Disease: The Systemic Synuclein Sampling Study (S4)
Objective: To characterize the distribution of alpha-synuclein (aSyn) pathology in multiple tissues and body fluids within the same Parkinson’s disease (PD) subjects and compared to…Serum glutamate is associated with the motor subtype of Parkinson’s disease
Objective: We aimed to study the concentration of glutamate in the serum of patients with Parkinson's disease (PD) and its connection with clinical variants of…PrP as a receptor of alpha-synuclein in the pancreas of patients with synucleinopathies
Objective: We have investigated whether the cellular prion protein interacts with alpha-synuclein in pancreatic cells of patients with synucleinopathies. Background: Neurodegenerative diseases such as Alzheimer’s…Microglial activation, white matter and hippocampal damage correlate with cognitive impairment in chronic cerebral hypoperfused and MPTP-lesioned mice
Objective: We hypothesize that cerebral hypoperfusion may influence the cognitive function of PD animal models. To investigate the effects of cerebral hypoperfusion and microangiopathy on…Correlation between mood and behavioral disorders and quality of life in patients with Parkinson’s disease
Objective: The aim of this study was to investigate if the mood and behavioral disorders could be correlate with quality of life in patients with…Parkinson’s disease anxiety is associated with Lewy bodies in the Anterior Cingulate
Objective: The goal of this study is to determine if there is an association between anxiety and the presence and regional distribution of Lewy bodies…Dissociate effect of dopaminergic therapy in reward expectation and prediction error in PD patients with comorbid impulse control disorder
Objective: To study EEG oscillatory activity associated to reward prediction error in Parkinson’s disease (PD) patients with impulse control disorders (ICD) and determine how dopaminergic…FuRST2.0: Development of a modified functional rating scale for use in premanifest and early-manifest Huntington’s disease
Objective: Develop a patient-reported outcome (PRO) modification of the Functional Rating Scale for pre-Huntington Disease (FuRST-pHD) using focus group, Delphi panel and cognitive pre-testing methodology.…
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