SAFINAMIDE IN DAILY CLINICAL PRACTICE: ASSESSMENT OF EFFICACY AND TOLERABILITY IN PARKINSON´S DISEASE
Objective: to analyze the long term efficacy and tolerability of safinamide added as adjunctive therapy in a series of patients with Parkinson´s disease (PD) Background:…Two novel ANO10 mutations causing adult-onset autosomal recessive spinocerebellar ataxia
Objective: Clinical and genetic characterization of a patient Background: In recent years mutations more than 100 different genes have been shown to underlie spinocerebellar ataxias.…Opsoclonus-myoclonus-ataxia syndrome associated to rubella
Objective: Reporting exceptional etiology of OMS and remembering spectrum of neurological manifestations of rubella. Background: Opsoclonus-myoclonus-ataxia (OMS) is a rare child clinical paraneoplastic syndrome. OMS…Respiratory Function and Functional Decline in Spinocerebellar Ataxia Type 2
Objective: To evaluate the relationship between the values of Peak Expiratory Flow rate (PEFr), Maximum Inspiratory Pressure (MIP), the presence of respiratory complaints with disease…Alignment of objective markers of speech with listener based judgements and disease severity in Friedreich ataxia
Objective: To identify a subset of acoustic markers of speech that objectively describe listener perceptions, disease severity and speech related quality of life in Friedreich…Post-pump chorea and progressive supranuclear palsy like syndrome following major cardiac surgery: A case series
Objective: We report three patients who developed movement disorders after major cardiac surgery and suggest a common underlying mechanism. Background: Choreiform movement disorder occurs in…The comparison of the clinical characteristics and treatment outcomes between non-troublesome and troublesome hemifacial spasm in 270 Thai patients
Objective: To compare the clinical characteristics and treatment outcomes after injecting Botulinum neurotoxin type A (BoNT-A) between non-troublesome and troublesome hemifacial spasm (HFS) in Thais.…Development of Mucoadhesive Sustained Release Floating Tablets of Silymarin using Natural Polymer for Improved Anti-Parkinson Efficacy
Objective: The objective of the present investigation was to develop Mucoadhesive sustained release floating tablets of Silymarin using natural polymers (Coccinia grandis and Rumex vasicarious)…Effect of dopamine D2-receptor antagonist and basal ganglia neuromodulation on neuronal activity in the cerebral motor area and cerebellar dentate nucleus
Objective: The effect of the D2-antagonist haloperidol on single unit activity (SU) and local field potentials (LFPs) of the cerebellar dentate nucleus and motor cortex…Treating Depression in Parkinson’s Disease: a Systematic Literature Review
Objective: To elucidate the most acceptable and effective treatments for the management of depression in Parkinson’s disease (PD) using a systematic review approach. Background: Depression…
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