Alignment of objective markers of speech with listener based judgements and disease severity in Friedreich ataxia
Objective: To identify a subset of acoustic markers of speech that objectively describe listener perceptions, disease severity and speech related quality of life in Friedreich…Post-pump chorea and progressive supranuclear palsy like syndrome following major cardiac surgery: A case series
Objective: We report three patients who developed movement disorders after major cardiac surgery and suggest a common underlying mechanism. Background: Choreiform movement disorder occurs in…The comparison of the clinical characteristics and treatment outcomes between non-troublesome and troublesome hemifacial spasm in 270 Thai patients
Objective: To compare the clinical characteristics and treatment outcomes after injecting Botulinum neurotoxin type A (BoNT-A) between non-troublesome and troublesome hemifacial spasm (HFS) in Thais.…Development of Mucoadhesive Sustained Release Floating Tablets of Silymarin using Natural Polymer for Improved Anti-Parkinson Efficacy
Objective: The objective of the present investigation was to develop Mucoadhesive sustained release floating tablets of Silymarin using natural polymers (Coccinia grandis and Rumex vasicarious)…Effect of dopamine D2-receptor antagonist and basal ganglia neuromodulation on neuronal activity in the cerebral motor area and cerebellar dentate nucleus
Objective: The effect of the D2-antagonist haloperidol on single unit activity (SU) and local field potentials (LFPs) of the cerebellar dentate nucleus and motor cortex…Isolated delusion in idiopathic Parkinson’s disease: particularities in a subgroup of patients
Objective: Characterize the subgroup of Parkinson’s Disease (PD) patients with isolated delusions. Background: Psychotic features in patients with PD, especially delusions, usually are thought to…Functional stiff person like disorders: clinical features and red flags
Objective: To delineate the characteristics and distinguishing features of functional stiff person-like disorders (fSPLD). Background: Stiff person spectrum disorders (SPSD) are a group of rare…Preoperative quantitative evaluation of psychological determinants in abnormal head postures
Objective: Improving the diagnostic capability by discriminating the psychogenic part of the disorder using a dedicated “home-made” questionnaire completed with the Minnesota Multiphasic Personality Inventory (MMPI).…Identification of aberrant circulating miRNAs in Parkinson’s disease plasma samples
Objective: To detect the aberrant expression of circulating miRNAs and explore thepotential early diagnostic biomarkers in patients with Parkinson’s disease (PD). Background: In the past…GBA p.Glu326Lys substitution increases the risk to develop Parkinson’s disease; is it enough to affect disease phenotype?
Objective: To evaluate the frequency of GBA p.Glu326Lys (E326K) carriers in a large cohort of Parkinson's disease patients of Ashkenazi Jewish origin (AJPD) and to…
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