Impact of OFF periods on aspects of employment for people with Parkinson’s disease
Objective: To characterize the impact of OFF periods on aspects of employment for people with Parkinson’s disease (PD) who have OFF periods compared to those…Association between hand functions, hand reaction time and balance in patients with idiopathic Parkinson’s disease
Objective: To investigate the relationship between hand function, hand reaction time and balance in patients with idiopathic Parkinson's disease (PD). Background: Symptoms of PD such…Is the personal Kinetigraph useful in the management of Parkinson´s disease patients? A retrospective study from a tertiary movement disorder center
Objective: To assess the usefulness of the Personal KinetiGraph (PKG) in characterizing the intensity and timing of motor symptoms in Parkinson´s Disease (PD) patients. Background:…CXCL12 is involved in α-synuclein-triggered neuroinflammation of Parkinson’s disease
Objective: Activated microglia and increased cytokine levels could precede neurodegeneration in neuro-inflammation in A53T mice, and CXCL12 was found increased in plasma CNS-derived exosomes, which…K0706, A Potent Orally Bioavailable Brain-Penetrating Selective Inhibitor of cABL Protein Tyrosine Kinase, Exhibits Neuroprotective Activity in Preclinical Models of Parkinson’s Disease
Objective: Preclinical assessment of K0706, a potent c-Abl inhibitor, as a neuroprotective disease modifying agent for the treatment of Parkinson’s disease (PD) related neurodegeneration using…Effects of levodopa on LTP-like plasticity induced by quadripulse magnetic stimulation in Parkinson’s disease
Objective: To study LTP-like effect induced by QPS on primary motor cortex of PD patients in “on” or “off” medication state and reveal the relationship…Multiple system atrophy with predominant striato-nigral degeneration (MSA-P) and TDP-43 pathology: an unusual pathologic variant of MSA
Objective: To report a patient with MSA with concomitant occurrence of TDP-43-labeled and a-synuclein labeled inclusions in oligodendrocytes. Background: The pathologic hallmark in multiple system atrophy…The effect of baseline cognitive status of Parkinson’s disease on the outcome after deep brain stimulation surgery
Objective: To evaluate the effect of baseline cognitive status of Parkinson’s disease (PD) on the outcome after deep brain stimulation (DBS) surgery. Background: Advanced dementia…Association of Charcot-Marie-Tooth disease, Parkinson’s disease and FIG4 mutations
Objective: Here we report a patient with Charcot-Marie-Tooth (CMT) 4J disease (related to FIG4 mutations) who developed an early-onset Parkinson’s disease during evolution. Background: FIG4 encodes…Neuromelamin-MRI in patients with Pure Autonomic Failure
Objective: To assess the utility of neuromelanin-MRI (NM-MRI) methods in a prodromal alpha-synuclein disorder, Pure Autonomic Failure (PAF). Background: PAF is a peripheral alpha-synucleinopathy (AS)…
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