Comprehensive Screening of Genetic, Genomic, Mitochondrial, and Microbiome Associations with Phenotypic Measures in the Dominican Republic PKAN Cohort
Objective: Establish novel molecular predictors of phenotypic variation using screening of genomic, transcriptomic, mitochondrial, microbiome, and clinical features. Background: Pantothenate Kinase Associated Neurodegeneration (PKAN), also…Interrater Agreement for Movement Disorder Classification in Children with Mixed Movement Disorders
Objective: To determine interrater agreement on the classification component of the Movement Disorders-Childhood Rating Scale (MD-CRS). Background: The MD-CRS consists of three parts: classification, general assessment, and…SNCA hypomethylation in rapid eye movement sleep behavior disorder is a potential biomarker for Parkinson’s disease
Objective: We aimed to explore whether there were different distributions of α-synuclein at a genetic and/or protein level in patients with iRBD. Background: α-Synuclein has been related to…Sexual dysfunction associated with deep brain stimulation of the Globus Pallidus pars interna
Objective: To explore sexual dysfunction (SD) in a dystonia patient with deep brain stimulation of the Globus Pallidus pars interna (GPi DBS). Background: There is…Quality of life in ET and ET-plus patients with thalamic deep brain stimulation
Objective: To compare the quality of life (QOL) and activities of daily living (ADL) of patients with Essential Tremor (ET) and Essential Tremor plus (ET-p)…Subacute cognitive decline after DBS in a patient with idiopathic delayed-onset edema
Objective: To describe a patient who developed idiopathic delayed-onset edema (IDE) and cognitive decline three days after deep brain stimulation of subthalamic nucleus (STN-DBS). Background: IDE…Evaluation of the effect of Bilateral Subthalamic Nucleus Deep Brain Stimulation on fatigue in Parkinson’s disease
Objective: To determine the effect of subthalamic nucleus (STN) deep brain stimulation (DBS) on fatigue in PD patients. Background: Fatigue is a common and disabling…Overcoming Stimulation-Related Side Effects And Improving Outcome By Proper Programing Of Subthalamic Stimulation Of Parkinson’s Disease: Cases Report
Objective: We reported three cases of subthalamic deep brain stimulation (STN-DBS) of Parkinson’s disease (PD), with successful management of challenging issues during programing. Background: Proper…Single-energy Metal Artefact Reduction: a Precise Method for Localization of Deep Brain Stimulation Electrodes in Parkinson’s Patients
Objective: To determine placement of electrodes using the single energy metal artifact reduction (SEMAR) algorithm with a 320 multi-slice computed tomography (MSCT) volume scanner in…Inertial sensor-based kinematics in the differential diagnosis of Parkinson’s disease and atypical parkinsonisms
Objective: Assess the role of inertial sensors in the phenotyping and differential diagnosis of Parkinson’s Disease vs. Atypical Parkinsonisms Background: Wearable devices have been used…
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