Wearable Sensor-Driven Responsive Deep Brain Stimulation for Essential Tremor
Objective: To develop and clinically validate a responsive deep brain stimulation (R-DBS) paradigm – meaning stimulation would only be delivered when needed - driven by…Parkinson’s rest tremor disappearance after cerebellar hemorrhage
Objective: To present a case report of Parkinson's rest tremor disappearance after cerebellar hemorrhage. Background: Parkinson’s Disease (DP) clinical diagnosis relies on the presence of…Towards a better understanding of social work practice in Parkinson’s disease care
Objective: To understand and document the roles and utilization of clinical social workers (SW) in the care of Parkinson’s disease (PD). Background: The importance of an interdisciplinary and evidence-based approach to…Spinocerebellar ataxia (SCA) type 2 and type 8: a tale of two repeat expansions in a single patient
Objective: To describe the rare occurrence of coexisting SCA Types 2 and 8 in a pediatric patient. Background: SCAs are a group of autosomal dominant…Reversible hemichorea due to contralateral anterior cerebral artery territory hypoperfusion
Objective: We report hemichorea due to hypoperfusion of the contralateral anterior cerebral artery (ACA) territory (including caudate nucleus and its connections) that reversed with revascularization.…Pilot study to evaluate pimavanserin for the treatment of motor and behavioral symptoms of Tourette syndrome.
Objective: To determine whether pimavanserin has an effect on motor and behavioral aspects of Tourette syndrome (TS). Background: Pimavanserin is a serotonin 2A receptor inverse…Carboplatin, Paclitaxel, and Nivolumab-induced Parkinsonism Responsive to Levodopa
Objective: To present the first reported case of reversible, levodopa sensitive, chemotherapy- induced parkinsonism due to the combination of carboplatin, paclitaxel, and nivolumab. Background: Many case reports describe antineoplastic agents causing reversible parkinsonism, most commonly, cyclophosphamide, cytosine arabinoside, and cyclosporine. To our knowledge, drug-induced parkinsonism related to combination therapy of paclitaxel, carboplatin, and nivolumab has never been…A Phase 3 Trial Evaluating the Efficacy, Duration of Effect, and Safety of DaxibotulinumtoxinA for Injection in the Treatment of Cervical Dystonia
Objective: To evaluate the efficacy and safety of two doses of DaxibotulinumtoxinA for Injection (DAXI) vs placebo for treatment of cervical dystonia (CD). Background: DAXI…Analysis of dystonia and rating scales in children and young adults with SGCE myoclonus dystonia
Objective: The aim of this study was to analyze the clinical characteristics of dystonia (Axis I) and to explore rating tools for writing, walking and running…Whole genome sequencing aids in diagnosing GCH1 dopa responsive dystonia in two Peruvian patients and influences medical management
Objective: To describe the clinical features and treatment response of two Peruvian patients with GHC1 dopa responsive dystonia diagnosed by whole genome sequencing. Background: Pathogenic variants in…
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