MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2022 International Congress

    Dried blood and plasma spots for the measurement of neurofilament light chain and inflammatory cytokines in patients with REM sleep behaviour disorder

    B. Huxford, C. Simonet, L. Carbonell, A. Zirra, N. Vickaryous, A. Gill, A. Schrag, R. Dobson, A. Noyce (London, United Kingdom)

    Objective: The objective of this study was to investigate the relationship between plasma and dried blood/ plasma spot measurements of inflammatory markers (IFN-ɣ, IL-1β, IL-6,…
  • 2022 International Congress

    Physician satisfaction from continuous telemonitoring in Parkinson’s disease

    A. Ntanis, G. Rigas, K. Tsamis, A. Tsakanika, F. Kanellos, S. Konitsiotis, D. Fotiadis (Ioannina, Greece)

    Objective: This work presents an evaluation of the satisfaction of physicians from using a continuous telemonitoring system for patients with Parkinson’s disease (PD). Background: The…
  • 2022 International Congress

    Pilot study to investigate the use of in-clinic sensing to identify optimal stimulation parameters for deep brain stimulation therapy in Parkinson’s disease

    S. Lewis, S. Ojemann, D. Kramer, L. Hirt, E. Radcliffe, M. Case, A. Becker, R. Raike, J. Thompson, D. Kern (Boulder, USA)

    Objective: Compare the use of in-clinic sensing functionality and standard of care monopolar review for identifying optimal settings of a deep brain stimulation (DBS) in…
  • 2022 International Congress

    Parkinson`s disease in Pandemic Covid

    S. Galbineanu, A. Ailene (Brasov, Romania)

    Objective: SARS-CoV2 infection invades the brain through ACE2 receptors or the cytotoxic aggregation of proteins, including α-synuclein.Studies are uncertain on the risk of COVID and…
  • 2022 International Congress

    Parkin deficiency impairs mtDNA dynamics and propagates inflammation

    K. Wasner, S. Smajić, J. Ghelfi, S. Delcambre, C. Prada-Medina, E. Knappe, G. Arena, P. Mulica, G. Agyeah, A. Rakovic, I. Boussaad, K. Badanjak, J. Ohnmacht, J. Gérardy, M. Takanashi, J. Trinh, M. Mittelbronn, N. Hattori, C. Klein, P. Antony, P. Seibler, M. Spielmann, S. Pereira, A. Grünewald (Belvaux, Luxembourg)

    Objective: We sought to explore Parkin’s role in (i) averting neuronal mtDNA dyshomeostasis/release and (ii) the activation of downstream inflammatory processes. Background: Mutations in Parkin…
  • 2022 International Congress

    Initial Postmarketing Real World Experience with directSTIM™ DBS System: A Case Series

    W. Polanski, S. Sobottka, V. Coenen, A. Frank, B. Falkenburger (Dresden, Germany)

    Objective: In this study we report the first three cases of a new, CE-marked system for deep brain stimulation. Background: The PMCF study is a…
  • 2022 International Congress

    TWNK in Parkinson’s disease: a Movement Disorder and Mitochondrial Disease Center perspective study

    M. Percetti, G. Franco, E. Monfrini, L. Caporali, R. Minardi, C. La Morgia, M. Valentino, R. Liguori, I. Palmieri, D. Ottaviani, M. Vizziello, D. Ronchi, F. Di Berardino, A. Cocco, G. Comi, A. Albanese, B. Giometto, E. Valente, V. Carelli, A. Di Fonzo (Milano, Italy)

    Objective: The aim of the study was to screen for TWNK variants in an Italian cohort of Parkinson’s disease (PD) patients, and to assess the…
  • 2022 International Congress

    Involving people with lived experience of Parkinson’s in trial design: the EJS ACT-PD initiative

    M-L. Zeissler, N. Bakshi, M. Bartlett, A. Batla, D. Byrom, R. Chapman, E. Deeson, R. Ellis-Doyle, C. Gonzales-Robles, A. Jewell, H. Matthews, L. Miller, G. Mills, L. Mooney, A. Morgan, J. Rudiger, D. Salathiel, P. Scurfield, C. Siu, S. Whipps, S. Wonnacott, T. Foltynie, C. Carroll, K. Mcfarthing (Plymouth, United Kingdom)

    Objective: To maximally involve people with the lived experience of Parkinson’s in the design of the first multi-arm multi-stage (MAMS) trial for disease modifying therapies…
  • 2022 International Congress

    Intraoperative microelectrode recodings reveal functional structure of Globus Pallidus pars interna in dystonic patients

    A. Kaymak, M. Vissani, S. Rinaldo, R. Eleopra, L. Romito, A. Mazzoni (Pisa, Italy)

    Objective: We characterized the functional structure of Globus pallidus pars interna (GPi) in dystonic patients by analizing the distribution of the firing pattern features in…
  • 2022 International Congress

    The functional neuroanatomy of cortical slowing predicts clinical features of Parkinson’s disease

    A. Wiesman, E. Fon, S. Baillet (Montreal, Canada)

    Objective: Investigate the relevance of spatially-resolved estimates of cortical neural slowing for predicting clinical features of patients with Parkinson’s disease (PD). Background: In patients with…
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