Is Increased Mineralisation of Putamen Relevant for Pathophysiology of Cervical Dystonia?
Objective: To assess the susceptibility-weighted imaging in patients with idiopathic cervical dystonia Background: Susceptibility-weighted imaging (SWI) is an advanced MR imaging sequence that can be…Cannabis treatment in patients with Huntington’s disease in a clinic cohort was safe and effective
Objective: To estimate the safety and efficacy of Cannabis treatment in HD patients. Background: Huntington's disease (HD) is a neurodegenerative progressive disorder inherited in an…Treatment Selection in Multi-Arm Multi-Stage Clinical Trials in Parkinson Disease: The Search for the Ideal Neuroprotective Drug
Objective: The Edmond J Safra Accelerating Clinical Trials in Parkinson disease (PD) initiative (EJS ACT-PD) aims to accelerate the identification of disease modifying treatments for…EFFECTS OF OPICAPONE IN PARKINSON DISEASE AS ASSESSED BY KINEMATIC TECHNIQUES
Objective: We aimed to objectively investigate the effects of Opicapone on bradykinesia in Parkinson's Disease (PD) by kinematic analysis. Background: By increasing L-dopa bioavailability, catechol-O-methyl…Head injury prior to Parkinson’s disease predicts faster self-reported motor and cognitive decline
Objective: To compare rates of self-reported cognitive and motor decline in people with Parkinson’s Disease (PD) with and without a history of head injury (HI).…Sisters with a novel compound heterozygous mutation in GCH1 gene linked to dopa responsive dystonia
Objective: Objective: Two sisters with a diagnosis of dopa-responsive dystonia (DRD) with a new mutation are reported. Background: Background: GTP cyclohydrolase I (GCH1) mutations are…Perceptions of persons with Parkinson’s disease towards telemedicine as an alternative mode of consultation: An International Pre-Implementation Survey
Objective: To assess the preferences and perceptions of persons living with Parkinson’s disease (PD) towards virtual consultations as an option for out-patient consultations. Background: Global…Network detection and connectivity analysis to predict DBS-induced ataxia in essential tremor
Objective: We aim to differentiate networks associated with deep brain stimulation (DBS) induced ataxia in essential tremor (ET) patients and test if connectivity to these…Functional Rating Scale 2.0 (FuRST2.0), a patient reported outcome measure for Huntington’s disease: The importance of the patient voice in scale development
Objective: Use focus groups, a Delphi panel, and multiple iterations of cognitive pretesting to develop a patient-reported outcome (PRO) measure of function in Huntington’s disease…The non-motor features of essential tremor with midline distribution
Objective: To investigate the non-motor signs among essential tremor (ET) patients presenting with midline tremor (Mid-ET). Background: Midline essential tremor represents a distinctive group of…
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