Prevalence of Parkinson’s disease and Atypical Parkinsonisms in Colombia: Data from the national health registry 2016-2021
Objective: To estimate prevalence of Parkinson’s Disease (PD) and Atypical Parkinsonisms and characterise the diagnosed population in a country with a development economy Background: The…Diagnostic algorithm in recessive and sporadic early-onset ataxias
Objective: To develop a diagnostic algorithm that allows to differentiate recessive or sporadic ataxias by the clinical phenotype, biochemical markers and neuroimaging studies of the…Evaluation of α-synuclein pathology and function in dopaminergic neurons derived from LRRK2 I1371V PD patient iPSCs
Objective: To evaluate cellular pathogenesis in DA neuron function, and α-synuclein pathology using LRRK2-I1371V PD iPSC. Background: It is reported for complex-neurodegenerative disorders like PD,…Establishing and validating 1-methyl-2-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced zebrafish model of Parkinson’s disease
Objective: The current study aims to establish a zebrafish model of PD using MPTP neurotoxin and the validation of the MPTP effect through swimming behavior…Facial emotion recognition in Parkinson’s disease: the role of executive and affective domains
Objective: We aimed to explore facial emotion recognition (FER) skills in individuals with Parkinson’s disease (PD) by using a dynamic presentation of emotions across different…The prevalence of helicobacter pylori in Parkinson’s disease
Objective: to study the association between helicobacteriosis pylori (HP) and patients with Parkinson's disease Background: Helicobacter pylori is a bacterium associated with gastrointestinal diseases and…Mimics or multiplicity: two patients with a PSP phenotype and underlying genetic neurodegenerative disorders.
Objective: To describe a two cases of patients presenting with a PSP phenotype and genetic findings consisted with Huntington’s disease (HD) in one case and…Transcranial magnetic resonance-guided focused ultrasound in Lance-Adams syndrome
Objective: The objective is to present the first reported case of a patient with post-hypoxic myoclonus (PHM) who underwent noninvasive MR-guided Focused Ultrasound Treatment (MRgFUS).…A phase 2b, randomized, dose-response study of SAGE-324/BIIB124 for the treatment of essential tremor: KINETIC 2 trial in progress
Objective: The phase 2b KINETIC 2 trial is a double-blind, randomized, placebo-controlled, dose-response study designed to evaluate SAGE-324/BIIB124 (SAGE-324) for the treatment of patients with…Smoking and Substantia Nigra Neuron Density in the Presence and Absence of Lewy Pathology
Objective: Our objective is to examine the association of mid-life smoking with post mortem substantia nigra (SN) neuron density in the presence and absence of…
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