Diagnostic value of striatal [18F]-FP-DTBZ PET in Parkinson’s disease
Objective: To detect the difference of dopaminergic integrity between PDs and healthy controls (HC) using [18F]-FP-DTBZ PET in vivo and to obtain the diagnostic value…A motor-cognitive intervention impacts daily-living gait and activity in Parkinson’s disease fallers differently than a motor intervention: analysis using a machine learning approach
Objective: Applying machine learning (ML) to identify if there were clusters of daily-living gait and physical activity measures that differed among responders to the two…Long-term effects of bilateral STN-DBS on speech in Parkinson’s disease patients
Objective: To evaluate the long-term effects of bilateral STN-DBS on speech in advanced Parkinson’s disease (PD) patients. Background: Bilateral STN-DBS is an effective treatment in…Cognitive performances and autonomic dysfunction in MSA patients
Objective: This study aims to assess the cardiovascular autonomic profile in patients suffering from either MSA-P or MSA-C, and subsequently to explore a potential link…Social cognition in patients with cerebellar neurodegenerative disorders
Objective: The aim of this study was to investigate social cognition (SC) in patients with different cerebellar neurodegenerative disorders (CDs). Background: CDs are a heterogeneous…The relationship between sleep and Parkinson’s disease progression: A Mendelian Randomization study
Objective: The objective of the study was to determine the causality between sleep disorders and progression of motor and cognitive endpoints of Parkinson’s disease. Background:…Mitochondrial and autophagy alteration in a new fatty acid hydroxylase-associated neurodegeneration (FAHN) model
Objective: Establishing a FAHN Drosophila model to identify cellular disease mechanisms. Background: Fatty acid hydroxylase-associated neurodegeneration (FAHN) is an early-onset neurodegenerative disease that manifests brain…To Prescribe or Not to Prescribe: Assessing the impact of Parkinson’s nurse prescribers
Objective: Within the UK, after successful completion of a formally recognised programme Parkinson’s Nurse Specialists (PNS) can act as independent prescribers, and as part of…Isolated craniocervical dystonia without neuropsychiatric manifestations associated with NMDA-receptor antibodies
Objective: N-methyl-D-aspartate receptor (NMDAR) encephalitis classically spans neuropsychiatric disturbance, autonomic dysfunction and salient movement disorders. Attenuated presentations are increasingly recognised; however, presentations with an isolated…Pallidal firing rate and alpha oscillations correlate with the severity of clinical symptoms in patients with dystonia
Objective: To examined how pallidal activity correlates with symptom severity across dystonic patients. Background: The internal segment of globus pallidus (GPi) is the most common…
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