Design of a prodromal screening study for subtypes in Parkinson’s Disease
Objective: To follow-up prodromal Parkinson’s Disease (PD) subtypes in a longitudinal cohort study, validating new biomarkers and ethical guidelines for early detection of PD. Background:…Clove mediated Rescue in Parkinson’s Disease involves modulation of p53 and Sestrin2 in SHSY5Y cell line model
Objective: The study analyzed the neuroprotective effect of ethanolic extract of clove against Parkinson’s disease (PD) type toxicity in SHSY5Y cell line model and interrogation…Caregiver burden in Parkinson’s Disease patients with Cardiovascular Dysautonomia
Objective: We sought to estimate the impact of cardiovascular autonomic neuropathy (cAN) on informal caregivers of patients with Parkinson’s disease (PD), defined as individuals providing regular…A Potential Cluster Near Site of Dry Cleaning Contamination
Objective: To characterize specific health outcomes of people with potential exposure to chemicals used in dry cleaning. Background: Trichloroethylene (TCE) is a chlorinated solvent used…Tissue Frataxin Increases After Administration of CTI-1601, a Frataxin Replacement Therapy in Development for the Treatment of Friedreich’s Ataxia
Objective: To evaluate the pharmacodynamic (PD) and safety profiles of subcutaneous (SC) administration of multiple ascending doses of CTI-1601 in patients age ≥18 years with…Increased alpha-synuclein level in primary macrophages derived from patients with Parkinson’s disease
Objective: To assess glucocerebrosidase and alpha-synuclein level in primary macrophages derived from patients with Parkinson’s disease with and without GBA1 mutation. Background: Parkinson’s disease (PD)…Autonomic dysfunction and its correlation witn synucleinopathy: an immunohistological study in Tunisian patients with parkinson disease
Objective: Identify autonomic digestive symptoms of Parkinson disease (PD)Identify correlations between autonomic dysfunction and alpha-synuclein immunochemical staining in the upper digestive tract. Background: Pathological processes…NPC1 is not a PD risk factor gene
Objective: To test the hypothesis of NPC1 to be a PD risk factor gene. Background: The many etiologies of PD include genetic risk factors. The…Objective and easily performed assessment of fine motor skills to support the differential diagnosis of Parkinson’s disease and other movement disorders with tremor
Objective: To assess the ability of a handheld device and its accompanying data analytics to distinguish between Parkinson’s disease (PD) and other tremor disorders. Background:…Verifying imaging accuracy for targeting and lead positioning in DBS: a phantom study.
Objective: In this phantom study we created an overview of the accuracy of four different modalities frequently used in DBS surgery and investigated the influence…
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