Deep Learning Approaches for Recognition of Parkinson’s Disease Patients through Handwriting, Audio and Video Analysis
Objective: The aim of this study was to build PD diagnostic models based on deep learning approaches using technologies including handwriting identification, automatic speech recognition…Exploring the impact of central cholinergic dysfunction on cognitive functioning in patients of Parkinson’s disease with and without REM sleep behavior disorder
Objective: This paper aims at establishes the presence of significantly higher cholinergic dysfunction in patients using short latency afferent inhibition. Background: Parkinson's disease (PD) is…PLA2G6-related dystonia-parkinsonism in identical twins manifesting at an advanced age: a case report and review of the literature.
Objective: To report a rare presentation of a rare disease and illustrate the range of phenotype seen in PLA2G6-associated dystonia-parkinsonism (PLADP). Background: PLA2G6 encodes a…Effectiveness of a home-based exercise program on gait characteristics in an individual with Parkinson’s disease over a one-year period: A case study
Objective: The purpose of this study was to explore the case history of an individual with Parkinson’s disease (PD) who used a home-based exercise programme…Isolated ZIC4 antibody associated paraneoplastic cerebellar degeneration
Objective: Anti-ZIC4 antibodies have recently been associated with paraneoplastic cerebellar degeneration (PCD) and are usually associated with small cell carcinoma lung. However, most of the…Machine learning-based classification of SCA1, SCA2, and Healthy controls using graph features
Objective: To differentiate genetic variants of spinocerebellar ataxia (SCA1 and SCA2) and healthy controls using machine learning on resting-state functional Magnetic Resonance Imaging graph features.…Plasma p-Tau181 and p-Tau231 in Parkinson’s Disease
Objective: To explore whether plasma phosphorylated tau (p-Tau) 181 and p-Tau231 levels are associated with cognition in a Parkinson’s Disease (PD) cohort. Background: We recently…Second Project: The feasibility and efficacy of virtual visits compared to in-person visits for management of Parkinson’s disease. A pilot, international, longitudinal, multicenter trial (NCT04695353).
Objective: To investigate the feasibility and efficacy of virtual visits for Parkinson's Disease (PD) compared to in-person visits. Background: Considering the limited access to specialists…Type 2 diabetes-associated transcriptomic changes in Parkinson’s disease and non-neurodegenerative control brains.
Objective: To evaluate the effect of type 2 diabetes (T2D) on gene transcription in Parkinson’s disease (PD) and non-neurodegenerative control brains. Background: People with T2D…Dynamical modulations of low frequency deep brain stimulation on axial symptoms in Parkinson’s disease
Objective: First, we aimed to evaluate the optimal contact to address axial symptoms with low frequency deep brain stimulation (LFS). Second, we aimed to evaluate…
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