A Potential Cluster Near Site of Dry Cleaning Contamination
Objective: To characterize specific health outcomes of people with potential exposure to chemicals used in dry cleaning. Background: Trichloroethylene (TCE) is a chlorinated solvent used…Tissue Frataxin Increases After Administration of CTI-1601, a Frataxin Replacement Therapy in Development for the Treatment of Friedreich’s Ataxia
Objective: To evaluate the pharmacodynamic (PD) and safety profiles of subcutaneous (SC) administration of multiple ascending doses of CTI-1601 in patients age ≥18 years with…Increased alpha-synuclein level in primary macrophages derived from patients with Parkinson’s disease
Objective: To assess glucocerebrosidase and alpha-synuclein level in primary macrophages derived from patients with Parkinson’s disease with and without GBA1 mutation. Background: Parkinson’s disease (PD)…Autonomic dysfunction and its correlation witn synucleinopathy: an immunohistological study in Tunisian patients with parkinson disease
Objective: Identify autonomic digestive symptoms of Parkinson disease (PD)Identify correlations between autonomic dysfunction and alpha-synuclein immunochemical staining in the upper digestive tract. Background: Pathological processes…NPC1 is not a PD risk factor gene
Objective: To test the hypothesis of NPC1 to be a PD risk factor gene. Background: The many etiologies of PD include genetic risk factors. The…Objective and easily performed assessment of fine motor skills to support the differential diagnosis of Parkinson’s disease and other movement disorders with tremor
Objective: To assess the ability of a handheld device and its accompanying data analytics to distinguish between Parkinson’s disease (PD) and other tremor disorders. Background:…Verifying imaging accuracy for targeting and lead positioning in DBS: a phantom study.
Objective: In this phantom study we created an overview of the accuracy of four different modalities frequently used in DBS surgery and investigated the influence…Sensorimotor retraining program based on the principles of S.P.R.Int (SensoriMotor perceptive Integrated) in association with E.M.D.R (Eye Movement Desensitization and Reprocessing): a new proposal for treatment in Functional Movement Disorders (FMD)- a case report
Objective: To propose a new multidisciplinary rehabilitation program based on association of sensorimotor retraining and EMDR to treat FMD. Background: There is an emerging new…Long-term Deutetrabenazine Safety on Motor, Psychiatric, and Cognitive Measures in Individuals With Chorea Associated With Huntington Disease
Objective: To evaluate long-term deutetrabenazine safety on motor, psychiatric, and cognitive measures in participants with chorea associated with Huntington disease (HD). Background: Deutetrabenazine, a vesicular…Baseline Characteristics and Treatment Patterns of a Global Huntington Disease Population Stratified by Chorea Severity
Objective: To describe baseline characteristics and treatment patterns in patients with chorea associated with Huntington disease (HD) by severity of chorea. Background: Though multiple treatment…
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