The natural history of Parkinson’s disease in LRRK2 G2019S carriers
Objective: To document differences between the evolution of self-reported symptoms and prodromal markers in LRRK2 G2019S carriers and non-carriers with and without Parkinson’s Disease (PD).…Can very early levodopa prevent self-injury in Lesch-Nyhan Disease?
Objective: To determine whether levodopa treatment starting at a very young age can prevent the development of the full clinical phenotype in Lesch-Nyhan disease. Background:…Severe tacrolimus-induced parkinsonism after kidney transplantation
Objective: To describe a kidney transplant recipient with severe tacrolimus-induced parkinsonism. Background: Kidney transplant recipients have to adhere to strict immunosuppressive regimens, which generally include…Longitudinal free-water changes in dementia with Lewy bodies
Objective: To characterize longitudinal diffusion microstructural changes in individuals with dementia with Lewy bodies (DLB). Background: Diffusion-weighted MRI (dMRI) examines tissue microstructure integrity in vivo.…Drivers of longitudinal healthcare cost in Parkinson Disease
Objective: To identify associations between baseline patient and disease characteristics, and longitudinal healthcare costs in Parkinson disease (PD). Background: Disease prevalence, disability-adjusted life-years, and PD…Neurological symptom severity in Wilson disease is associated with increased white matter mean diffusivity
Objective: To evaluate the relationship between white matter (WM) changes and neurological impairment in Wilson disease (WD). Background: Neuroimaging biomarkers derived from diffusion tensor imaging…Touchscreen nQ application as a remote digital biomarker in Parkinson disease
Objective: To characterize the viability of nQ machine learning platform via touchscreen keyboard as a digital biomarker for Parkinson disease Background: To date, a reliable…Intrarater and interrater reliability of the 3 meter backward walk test in individuals with Parkinson disease.
Objective: Determine the intrarater and interrater reliability of the three meter backward walk (3 MBW) test for individuals diagnosed with Parkinson Disease. Background: Background- Parkinson…Serum Metabolomics in Parkinson’s Disease: Correlations with Fecal Microbiome, Fecal Metabolomics and Clinical Status
Objective: To investigate the correlations between serum metabolites with fecal microbiome, fecal metabolites, and clinical phenotypes in patients with Parkinson’s disease (PD). Background: There is…Relationship between sleep quality, fear of fall and falls history in people with Parkinson’s disease
Objective: We aimed to investigate the relationship of sleep quality with falls and fear of fall (FOF) in people with Parkinson's disease (PwPD). Background: Fall…
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