MDS Virtual Congress 2021 Archives - Page 74 of 132

LRRK2 Inhibition by BIIB122 / DNL151: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Ph 1 Healthy Volunteer and Ph 1B Parkinson’s Disease Trials

D. Jennings, J. Wetering Derooij, M. Vissers, J. Heuberger, G. Groeneveld, R. Macuica, A. Kay, M. Borin, B. Wong, V. Daryani, S. Huntwork-Rodriguez, P. Chin, C. Ho, M. Troyer (South San Francisco, USA)
LY-487,379 alleviates parkinsonism when administered as monotherapy in the MPTP-lesioned marmoset

I. Frouni, C. Kwan, S. Nuara, S. Belliveau, A. Hamadjida, W. Kang, D. Bédard, J. Gourdon, P. Huot (Montreal, Canada)
LY-487,379 enhances the anti-parkinsonian action of a low dose of L-DOPA in the MPTP-lesioned marmoset

C. Kwan, I. Frouni, S. Nuara, S. Belliveau, A. Hamadjida, W. Kang, D. Bédard, J. Gourdon, P. Huot (Montreal, Canada)
Lysosomal storage disorder genes variants in Parkinson’s disease: a large cohort study in Chinese mainland population

Y. Zhao, H. Pan, Y. Wang, Z. Liu, Q. Zeng, Z. Fang, K. Xu, Z. Wang, X. Zhou, R. He, B. Li, G. Zhao, Q. Xu, Q. Sun, X. Yan, J. Tan, J. Li, J. Guo, B. Tang (Changsha, China)
Machine Learning (ML) Prediction of Parkinson’s Disease (PD) Risk and Nigral Neuron Density

I. Karabayir, L. Butler, S. Goldman, R. Kamaleswaran, F. Gunturkun, R. Davis, GW. Ross, H. Petrovitch, K. Masaki, C. Tanner, G. Tsivgoulis, A. Alexandrov, O. Akbilgic (Maywood, USA)
Maintenance of physical activity (PA) mitigates worsening of patient-reported outcomes in Parkinson’s disease (PD) during the COVID-19 pandemic

J. Morley, I. Subramanian, J. Farahnik, L. Mischley (Philadelphia, USA)
Management of tremor secondary to MORC2 related neurodevelopmental disorder with deep brain stimulation

M. Hull, D. Curry, M. Parnes (Houston, USA)
Mapping intrinsically photosensitive retinal ganglion cells (ipRGCs) dysfunction in patients with Parkinson disease using Chromatic pupilloperimetry

T. Fay-Karmon, D. Jaber, I. Sher, S. Zorani, A. Bleterman, Y. Rotenstreich, S. Hassin-Baer (Ramat Gan, Israel)
Mapping regional alpha-synuclein seeding capacity in Multiple System Atrophy

I. Martinez-Valbuena, N. P. Visanji, A. Kim, S. Lee, S. Alshimemeri, R. So, A. Gao, J. C. Watts, A. Lang, G. G. Kovacs (Toronto, Canada)
MAPT mutation frontotemporal dementia with parkinsonism: when previous results can skew the diagnosis

R. Franco, TC. Aguiar, A. Morganho, P. Lobo, R. Dias, S. Aguiar (Funchal, Portugal)