2025 International Congress » MSA, PSP, CBS: Biomarkers (non-neuroimaging)

4R-TAU seed amplification assay discriminates tauopathies from non-tauopathies and CBD from PSP in post-mortem brain samples

L. de Mena, M. Fernandez, J. Perez, C. Painous, A. Camara, A. Perez-Soriano, L. Molina-Porcel, E. Artikis, B. Caughey, Y. Compta (Barcelona, Spain)

Altered Tryptophan Metabolism and the Role of the Kynurenine Pathway in Multiple System Atrophy

R. Nagao, K. Kawabata, Y. Mizutani, H. Watanabe (Toyoake, Japan)

Anal Sphincter EMG changes can Progress over Time and can be considered as a Prognostic Marker in MSA

L. Lei, J. Bermejillo, P. Malladi, J. Panicker, A. Batla (London, United Kingdom)

Cutaneous Phosphorylated Alpha-Synuclein Deposition in Multiple System Atrophy

R. Freeman, T. Levine, B. Bellaire, C. Gibbons (boston, USA)

Disease Characteristics of the First 100 Participants in the CurePSP Genetics Program Cohort

C. Obasi, V. Zhao, C. Martinez, S. Scholz, H. Morris, N. Mcfarland, M. Nance, J. Wang, N. Mencacci, B. Cuoto, T. Foroud, J. Verbrugge, A. Miller, L. Heathers, L. Honig, A. Lang, F. Rodriguez-Porcel, P. Moretti, M. Mesaros, J. Brummet, K. Diaz, A. Wills (Boston, USA)

Gait Variability is Associated with Executive Function in Progressive Supranuclear Palsy

A. D'Souza, C. Sotirakis, J. Fitzgerald, C. Antoniades (Oxford, United Kingdom)

Interlaboratory cross-validation of CSF α-synuclein seeding aggregation assay for parkinsonisms

J. Perez-Montesino, M. Fernandez, R. Ruiz-Garcia, L. Naranjo, C. Painous, A. Camara, A. Perez-Soriano, L. de Mena, Y. Compta (Barcelona, Spain)

Is Urinary Retention a Marker of Possible Prodromal MSA in PAF?

E. Manzoni, I. Cani, G. Carrozzo, G. Giannini, L. Sambati, L. Baldelli, P. Guaraldi, P. Cortelli, G. Calandra-Buonaura (Bologna, Italy)

Low Level of Serum Total Cholesterol Predicts Mortality in Early-stage Multiple System Atrophy: a Prospective-cohort Study

JX. Huang, LY. Zhang, QR. Jiang, SC. Wang, Y. Xiao, NN. Che, JY. Lin, B. Zhao, YF. Cheng, CY. Li, HF. Shang (Chengdu, Sichuan, China)

MicroRNA Landscape of Multiple System Atrophy: Insights from Plasma and Patient-Derived Induced Pluripotent Stem Cell Models

K. Kuo, C. Chen, L. Lin, W. Wu (Taipei, Taiwan)

Multiscale entropy: a New Oculomotor Measure of PSP.

C. O'Keeffe, A. Gallagher, J. Inocentes, B. Coe, B. White, D. Brien, D. Munoz, R. Walsh, T. Lynch, C. Fearon (Dublin, Ireland)

Peripheral unspecific inflammatory parameters – not always useful in differential diagnosis of parkinsonian syndromes.

N. Madetko-Alster, P. Alster (Warsaw, Poland)

Plasma Neurofilament Light Chain and Orthostatic Hypotension in Isolated REM Sleep Behavior Disorder: A Biomarker for α-Synucleinopathy Progression

A. Calculli, D. Di Martino, P. Grillo, G. Bellini, C. Fazio, D. Comolli, D. Hoxhaj, S. Cerri, M. Terzaghi, A. Pisani (Pavia, Italy)

Plasma tau-species-containing neuron-derived extracellular vesicles as potential biomarkers for progressive supranuclear palsy

YC. Zheng, HH. Cai, WY. Kou, ZW. Yu, T. Feng (Beijing, China)

Proteome-Wide Association Study Identifies Plasma β-Glucuronidase as a Causal Risk Protein for Multiple System Atrophy

X. Chen, X. Wang, B. Wang, W. Luo (Hangzhou, China)

Proteomic analysis identifies GGA1, SCP2, and RABEPK as risk protein of multiple system atrophy

B. Ke, C. Li, X. Zheng, Y. Xiao, S. Wang, Q. Jiang, J. Lin, J. Huang, H. Shang (Chengdu, China)

Quantitative Gait Evaluation in Multiple System Atrophy: Supervised versus Unsupervised Analysis

F. Marchand, J. Labreuche, T. Ollivier, D. Guehl, A. Delval, L. Defebvre, AK. Berger, J. Wiedemann, L. Kjaersgaard, T. Warlop, A. Fasano, BR. Bloem, D. Devos, C. Moreau (Lille, France)

Relationship Between Alpha-Synuclein Aggregation Profiles, Imaging Biomarkers, and Disease Severity in a Phase 2 Study of ATH434 in MSA

M. Bradbury, P. Trujillo, K. Hett, C. Wong, C. Lucas, K. Kmiecik, D. Stamler, D. Claassen (Newark, USA)

The Sedentary Index (SI) for Daily Life Activity Monitoring in Progressive Supranuclear Palsy (PSP)

M. Dale, C. Silva-Batista, A. Ragothaman, Z. Nhem, A. Lawston, G. Harker, D. Maxwell, C. Speirs, D. Loudon, M. Mancini (Portland, USA)

Tracking Progression and Survival in a Large Cohort of Patients with Progressive Supranuclear Palsy

DP. Vaughan, R. Real, RG. Fumi, M. Theilmann Jensen, T. Revesz, Z. Jaunmuktane, T. Warner, A. Church, P. Leigh, E. Jabbari, H. Zetterberg, AJ. Heslegrave, E. Veleva, O. Swann, B. Ghosh, M. Hu, C. Kobylecki, P. Study Group, J. Rohrer, JB. Rowe, HR. Morris (London, United Kingdom)