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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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2026 International Congress » MSA, PSP, CBS: Biomarkers (non-neuroimaging)

Meeting: 2026 International Congress

A CSF C Terminal α Synuclein Assay to Differentiate Multiple System Atrophy From Parkinson’s Disease

P. Kallunki, L. Hansen, J. Wiedemann, L. Rørbæk Olsen, F. Schalk, N. van Demerbel (Valby, Denmark)

An Elevation in the Serum Biomarker pTau-181 May Identify Progressive Supranuclear Palsy Pathology

K. Ramirez (Redwood City, USA)

Automated Speech Analysis for the Differentiation of Multiple System Atrophy from Parkinson’s Disease in an English-Speaking Cohort

E. Ní Chonchúir, C. Espinoza Vinces, X. Yang, C. O'Keeffe, J. Inocentes, A. Gill, C. Fearon, R. Reilly (Dublin, Ireland)

Beyond α-Synuclein SAA: A Multimodal Minimally Invasive Platform for Biologically Informed Diagnosis of Parkinsonian Syndromes

I. Martinez-Valbuena, M. Abarghouei, D. Olszewska, S. Weber, S. Schnell, M. Sousa, D. Di Luca, N. Reyes, SM. Fereshtehnejad, J. Ta, C. Anastassiadis, J. Li, J. Sasitharan, N. Visanji, S. Fox, B. Mollenhauer, C. Tartaglia, G. Kovacs, A. Lang (Toronto, Canada)

Biomarker-Informed Survival Modelling Using Plasma Neurofilament Light and Clinical Predictors in a Prospective Multiple System Atrophy Cohort

V. Chelban, L. Lei, C. Lee, Y. Goh, I. Karagoz, R. Lee, H. Morris, N. Vijiaratnam, T. Foltynie, H. Houlden (London, United Kingdom)

Comprehensive Diagnostic Accuracy of α-Synuclein Seed Amplification Assays Across Non-Parkinsonian Synucleinopathies: A Systematic Review and Diagnostic Meta-analysis

P. Bhatele, P. Kukkle (Bangalore, India)

Data-driven operational definition of square-wave jerks to optimize diagnostic discrimination of progressive supranuclear palsy

D. Nguyen (Brisbane, Australia)

Fluid Biomarker Signatures in Atypical Parkinsonian Syndromes: Insights into Neurodegeneration and Clinical Heterogeneity

R. Yadav, R. Kumar, S. Dey, A. K, G. Tv, M. Harish, V. Holla, R. Mahale, N. Kamble, P. Mailankody, A. Mehta, M. Debnath, S. Subramanian, P. Pal (Bengaluru, India)

Fluid Biomarkers and the 4R-Tauopathies

C. Fogliano, ML. Nasi, S. Cauzzo, R. Manara, F. Pistonesi, E. Fiorenzato, M. Carecchio, W. Meissner, R. Biundo, M. Campagnolo, A. Antonini (Padova, Italy)

Identification of Alpha-synuclein Pathology in Primary Tauopathies by Seed Amplification Assay

C. Farris, S. Weber, Y. Ma, M. Starke, D. Irwin, A. Siderowf, B. Mollenhauer, L. Concha (Kassel, Germany)

Identification of Candidate Cerebrospinal Fluid Biomarkers in Multiple System Atrophy Using Mass Spectrometry‑Based Proteomics in CSF Biobank Samples

P. Kallunki, M. Lubas, J. Fussing Tengberg, V. Carmelo, S. Virreira Winter, P. Geyer (Valby, Denmark)

Molecular Profiling of Brain-Derived Extracellular Vesicles and Fluid Biomarkers in Parkinsonism: Distinct Signatures and Clinical Correlates in Progressive Supranuclear Palsy

A. Roy, S. Brahmachari, A. Pantelyat, L. Rosenthal, V. Dawson, T. Dawson (Baltimore, USA)

Olfactory Function as a Biomarker of Disease Progression in Progressive Supranuclear Palsy

Q. Shen, XY. Li, J. Wang, FT. Liu (Shanghai, China)

Pharmacogenomic Analysis of KM-819-Related Hepatotoxicity in Patients with Multiple System Atrophy

J. Han, R. Andrade, ES. Björnsson, JH. Lewis, MI. Lucena, S. Go, S. Stankeviciute, G. Aithal, G. Kim, C. Lee, C. Barlow, E. Kim (Bundang-gu, Republic of Korea)

Proteome-Wide Association and Mendelian Randomization Analyses Identify Plasma GUSB as a Potential Biomarker for Multiple System Atrophy

X. Wang, X. Chen, W. Luo (Hangzhou, China)

SCA27B and MSA-C with Positive Alpha-Synuclein Skin Biopsy – Case Report

R. Voshtina, J. Ng (Palo Alto, USA)

Towards Biomarker-Driven Staging of Multiple System Atrophy Using Longitudinal Neurofilament Light Profiling

L. Lei, R. Lee, P. Korlipara, V. Chelban, H. Houlden (London, United Kingdom)

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