Survival and risk of mortality of synucleinopathies: A 15 years population-based study (1991 – 2005)
Objective: To investigate the survival and mortality of synucleinopathies 15 years of study. Background: Limited data are available to estimate the mortality and the causes…Mitochondrial response precedes intracellular accumulation of α-synuclein in Parkinson’s disease
Objective: To investigate the expression of mitochondrial COX-IV during the progression of Parkinson's disease. Background: Parkinson's disease (PD) is a neurodegenerative disease characterized by the…Utility of the Mayo sleep questionnaire in predicting final autopsy diagnosis of alpha-synucleinopathy
Objective: To ascertain the utility of the MSQ in predicting final autopsy diagnosis of an alpha-synuleinopathy. Background: Idiopathic REM sleep behavior disorder (iRBD) is a…sFIDA: A sensitive diagnostic assay for quantification of α-synuclein aggregates
Objective: Optimizing of our sFIDA (surface-based fluorescence intensity distribution analysis) assay for specific detection and quantification of single α-synuclein aggregates. Background: Parkinson's disease (PD) is…Alpha-synuclein – super-resolution microscopy reveals potential new role of alpha-synuclein at the pre-synapse
Objective: Alpha-synuclein is a major key player in Parkinson's disease, however its physiological function still remains elusive. Using super-resolution microscopy this study aims to analyse…Gender-dependent behavioral and biochemical differences in the A53T genetic mouse model of Parkinson’s disease
Objective: The main aim of the present study was to investigate whether behavioral and biochemical differences may occur between male and female old (12-month-old) transgenic…
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