ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways
Objective: Endosomal sorting required for transport (ESCRT) orchestrates endo-lysosomal soring of ubiquitinated proteins, multivesicular body formation. The aim of this study is to elucidate the…Sleep motor activity in amyotrophic lateral sclerosis
Objective: To analyze quantitatively and with the most recent and advanced tools the presence of periodic leg movements during sleep (PLMS) PLMS and/or REM sleep…Association of amyotrophic lateral sclerosis with basal ganglia impairment
Objective: The aim of this study is to define extent of basal ganglia involvement in amyotrophic lateral sclerosis (ALS). Methods: The study included 45 patients…CSF level of chromogranin A in amyotrophic lateral sclerosis
Objective: Today the diagnosis of amyotrophic lateral sclerosis (ALS) is based on clinical assessment of upper and lower motor neuron signs in the limb and/or…ECG-based cardiopulmonary coupling for sleep stability assessment in patients with amyotrophic lateral sclerosis
Objective: The goal of this preliminary study is to introduce the technique of CardioPulmonary Coupling (CPC) to visualize and quantify the sleep spectrograms of Amyotrophic…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.