A Tiered Fecal Biomarker Approach to Identify Gut–Brain Axis Phenotypes in Young-Onset Parkinsonism in a Clinical Setting with Limited Resources
Objective: To explore the feasibility of a tiered fecal biomarker testing approach to identify potential gut–brain axis phenotypes in patients with young-onset parkinsonism in a…Autonomic Coupling Patterns Differ by REM Sleep Behavior Disorder Status in De Novo Parkinson’s Disease
Objective: To investigate the relationships between autonomic dysfunction, clinical severity, and striatal dopaminergic deficits in de novo Parkinson’s disease (PD), and to determine whether these…5-year Longitudinal Changes in Non-motor Symptoms and Their Association With Motor Progression in Parkinson’s Disease
Objective: To examine longitudinal relationships between non-motor symptoms (NMS) and motor progression in Parkinson’s disease (PD), and to determine whether baseline NMS predict motor decline…Exploring the Relationship Between Insomnia and Autonomic Dysfunction in Parkinson’s Disease: A 1 Year SCOPA-AUT Analysis
Objective: To evaluate the progression of autonomic dysfunction over one year in patients with Parkinson’s disease (PD) with and without comorbid insomnia. Background: Insomnia and…Cognitive & Clinical Correlates of Quality of Life in Probable Progressive Supranuclear Palsy
Objective: To examine the relationship between cognitive, executive, motor & autonomic function, neuropsychiatric symptoms, and health-related quality of life (HRQoL) in patients with progressive supranuclear…Severe Gastroparesis and Atypical Parkinsonism as Presenting Features of Neuronal Intranuclear Inclusion Disease (NIID)
Objective: To report a case of adult-onset neuronal intranuclear inclusion disease (NIID) presenting with progressive gait instability, neurogenic bladder, and life-threatening gastrointestinal dysmotility. Background: NIID…The influence of probable rapid eye movement sleep behavior disorder on PD-related motor and non-motor symptoms and multiple functional outcomes among Chinese community-dwelling elderly population
Objective: To investigate associations of probable REM sleep behavior disorder (pRBD) with Parkinson's disease (PD)-related symptoms and functional outcomes in Chinese older adults. Background: The…Assessment of dysautonomia in patients with sporadic adult-onset ataxia
Objective: The aim of this study was to assess prevalence and severity of autonomic dysfunction in patients with SAOA, defined as a subacute or progressive…Longitudinal Changes and Clinical utility of the Neurological Pupillary Index in De Novo Parkinson’s Disease
Objective: To characterize longitudinal changes in pupillometric parameters in de novo Parkinson’s disease and explore their associations with clinical severity and disease progression. Background: Automated…Heart Rate Variability in Early Parkinson’s Disease
Objective: This study aimed to investigate the clinical relevance of heart rate variability (HRV), which may indicate underlying autonomic nervous system activity, in patients with…
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