Antibody-Induced Failure of Botulinum Toxin Therapy: Restart with Incobotulinumtoxina Offers a New Opportunity
Objective: To study whether incobotulinumtoxinA (INCO), a new, low-antigenicity botulinum toxin (BT) drug, increases BT antibody (BTAB) titers in patients with antibody-induced therapy failure (ABTF)…Efficacy and Safety of a 2 mL Dilution of AbobotulinumtoxinA Compared With Placebo in Adult Patients With Cervical Dystonia
Objective: To determine the efficacy and safety of a 500 U/2 mL dilution of aboBoNT-A as compared to placebo in patients with cervical dystonia (CD).…A Phase 2, Open-Label, Dose-Escalating Study to Evaluate the Safety and Preliminary Efficacy of Daxibotulinumtoxina for Injection (RT002) in Isolated Cervical Dystonia
Objective: To report preliminary 24-week outcomes of an open-label trial of daxibotulinumtoxinA for injection (RT002) for the treatment of isolated cervical dystonia (CD). (ClinicalTrials.gov ID: NCT02706795) Background:…Regional differences may influence the drivers of change in Toronto Western Spasmodic Rating Scale (TWSTRS) scores following botulinum toxin treatment: Analysis of an international observational study
Objective: Investigate the drivers for change in Toronto Western Spasmodic Rating Scale (TWSTRS) scores in subjects with cervical dystonia (CD) following a single injection of…Cost-utility analysis of flexible interval incobotulinumtoxinA versus onabotulinumtoxinA in the management of blepharospasm and cervical dystonia in Ontario, Canada.
Objective: To carry out a cost-utility analysis for IncoBTX administered with flexible treatment intervals compared to OnaBTX in the management of BL and CD from…Impact of injection interval on patient satisfaction in the routine treatment of cervical dystonia with abobotulinumtoxinA
Objective: Evaluate the impact of injection interval on patient satisfaction with abobotulinumtoxinA (AboBoNT-A; Dysport®) over 1 injection cycle in patients with cervical dystonia (CD). Background:…Injection guidance use in the management of cervical dystonia with botulinum toxin
Objective: Investigate the use of injection guidance techniques and their impact on patient outcomes in the routine management of cervical dystonia (CD) with botulinum neurotoxin…Does GPi-DBS help non motor symptoms in cervical dystonia patients? A retrospective study of 17 patients
Objective: To study the efficacy of GPi DBS surgery in improving dystonia related severity, disability and pain as well as quality of life in medically…Structural and connectivity changes after botulinum neurotoxin therapy in blepharospasmus and hemifacial spasm
Objective: The two primary objectives of this study were to investigate the structural grey matter changes and connectivity differences between patients with BEB and HFS…Quality of life and epidemiological profile of patients undergoing botulinum toxin treatment
Objective: To trace a clinical and epidemiological profile of patients treated with botulinum toxin, evaluating the impact on quality of life. Background: The Botulinum Toxin…
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