Cognitive function and impulsive-compulsive behaviors in Parkinson’s disease motor subtypes
Objective: To investigate the differences in cognitive function between tremor-dominant (TD) and akinetic-rigid (AR) subtypes of Parkinson disease (PD). Background: Higher rates of dementia, autonomic symptoms,…Cognitive impairment in early onset and familial Parkinson’s disease.
Objective: The Parkinson’s Families Project (PFP) is a large-scale cohort of early onset (symptom onset <45) and familial Parkinson’s disease (PD) patients. One aim of…Resting state functional connectivity in PD patients with and without Freezing of gait
Objective: To investigate resting state functional connectivity (rsFC) abnormalities in patients with Parkinson's disease (PD), either with (PD-FOG) or without freezing of gait (PD no-FOG). …Cognitive Mechanisms of Visual Dysfunction in Non-Demented PD Patients (PD-ND)
Objective: To conduct a comprehensive assessment of visual processing in PD-ND, including tests of low-level vision sensitive to retinal pathology, high-level object/spatial vision reflecting ventral/dorsal…Cognitive effects of GPi versus STN deep brain stimulation in Parkinson’s Disease: experience with patients with moderate cognitive impairment
Objective: To compare the cognitive effects of GPi versus STN deep brain stimulation for PD in patients with moderate cognitive impairment. Background: Patients with moderate…Autosomal Dominant Spinocerebellar Ataxia Secondary to CACNA1G in a Patient of German Ancestry
Objective: We describe the case of a male patient of German ancestry with SCA 42. Background: Hereditary spinocerebellar ataxia (SCA) describes a heterogeneous group of…Validation of a performance-based assessment of functional ability related to cognition in Parkinson’s disease
Objective: Validate the University of California San Diego Performance-Based Skills Assessment (UPSA) in Parkinson's disease (PD) Background: Diagnostic criteria for PD dementia (PDD) require significant…Domain-specific impact of cerebral white matter hyperintensities on Parkinson’s disease cognitive functioning
Objective: In this study, we investigate the relationship between white matter hyperintensities (WMH) and Parkinson's disease (PD) cognitive impairment using a comprehensive neuropsychological battery with…Use of latent class analysis and growth mixture modeling to examine longitudinal neurocognitive trajectories in non-demented Parkinson’s disease
Objective: Examine the utility of latent class analysis (LCA) and growth mixture modeling (GMM) to elucidate cognitive phenotypes and longitudinal trajectories of cognitive change in…Association of the GBA T369M polymorphism with motor and cognitive symptoms in Parkinson’s disease
Objective: To determine whether the GBA polymorphism T369M is associated with earlier age of onset, lower cognitive performance, and more severe motor impairment in Parkinson's…
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