Cognitive Impairment in MSA Patients from the Catalan Multiple System Atrophy Registry (CMSAR)
Objective: To assess the cognitive function and its demographic and clinical correlates in MSA patients included in the Catalan Multiple System Atrophy-Registry (CMSAR). Background: Cognitive…Association of CSF biomarkers with motor and non-motor features in moderately advanced Parkinson’s disease cohort: the BioFIND study
Objective: Evaluate associations between CSF biomarkers of neurodegeneration and clinical phenotype in Parkinson’s disease (PD) participants of the BioFIND cohort. Background: Levels of CSF α-synuclein…Adding cues to a rat gambling task potentiates the increase in premature responding in response to chronic D2/3 agonist ropinirole without mitigating preference for risk
Objective: Investigating the effect of chronic administration of the dopamine D2/3 agonist ropinirole on a cued model of gambling behaviour in rats. Background: Dopamine D2/3 agonists…High systolic blood pressure is associated with cognitive impairment in Parkinson’s disease (PD)
Objective: To assess if metabolic risk factors are associated with cognitive dysfunction in PD patients. Background: Metabolic syndrome is known as a risk factor of many…Cognition in the PREDICT-PD Cohort
Objective: To identify whether there is evidence for cognitive dysfunction in participants identified as being at higher risk of Parkinson’s disease (PD) using the PREDICT-PD…Classification of neurocognitive impairment in Spanish speaking Parkinson’s disease patients
Objective: To examine differences between United States (US) and Latin American (LA) norms classifying cognitive impairment using standardized neuropsychological measures to assess cognition in Parkinson’s…Nilotinib differentially affects oligomeric α-synuclein and reduces phosphorylated neurofilaments and motor symptoms in Parkinson’s disease with dementia and Lewy body dementia
Objective: This is a retrospective biomarker study of an open-label clinical study to examine the safety and efficacy of lower doses (<50% of CML dose)…Connectivity patterns in frontal cognitive regions in Parkinson’s disease
Objective: Evaluate the changes in brain connectivity between Parkinson’s disease (PD) with and without mild cognitive impairment (MCI). Background: Up to 40% of PD patients…Neuropsychiatric and Cognitive Predictors of Early Diagnosis of Progressive Supranuclear Palsy
Objective: To define differences of neuropsychiatric and neuropsychological profile among Progressive Supranuclear Palsy (PSP) -Richardson syndrome (PSP-RS), PSP-parkinsonism (PSP-P), and Parkinson’s disease (PD), in order…Inhibition of long term memory and induction of biochemical deficits in rats following protofibrillar Aβ 1-42 injection
Objective: The present study was undertaken to study the effects of single intracerebroventricular (i.c.v.) injection of protofibrillar Aβ 1-42 on the long term memory Background:…
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