ASYMMETRIC EARLY-ONSET PARKINSONISM DUE TO PSEN1 MUTATION
Objective: To report a novel case of early-onset parkinsonism due to a presenilin 1 gene (PSEN1) mutation. Background: Mutations in PSEN1 gene are the most…Non-motor signs in essential tremor and essential tremor-plus syndromes
Objective: To investigate the non-motor profiles of essential tremor (ET) and essential tremor-plus (ET-plus) syndromes. Background: The recently established concept of differentiating ET from ET-plus…Head injury prior to Parkinson’s disease predicts faster self-reported motor and cognitive decline
Objective: To compare rates of self-reported cognitive and motor decline in people with Parkinson’s Disease (PD) with and without a history of head injury (HI).…The Unmet needs for advanced Parkinson Disease in -Patients’ during the Covid-19 pandemic in Israel
Objective: To evaluate the socio-demographic profile and clinical needs of advanced Parkinson's disease patients who were admitted to the neurological department at TASMC during the…A Milestone-based approach to monitoring disease progression in Parkinson’s disease
Objective: We used Parkinson Progression Marker Initiative (PPMI) data to assess the frequency of clinically meaningful disease milestones and examine baseline predictors of reaching these…Shannon entropy: a novel tool for assessing pentagon drawing in Parkinson’s disease
Objective: We used a digitizing tablet during PCT as a potential tool for assessing early cognitive deficits in PD yet without major cognitive impairment. We…Cognitive Impairment in Parkinson’s disease Patients: a Descriptive Study
Objective: This study aims to describe the cognitive profile in Parkinson's disease (PD) patients. Background: Cognitive impairment is a common non-motor symptom of PD. Cohort…Rapamycin attenuates nigral and hippocampal alpha-synuclein accumulation in AAV-mediated alpha-synuclein overexpression model of Parkinson’s disease
Objective: To examine the possible neurorestorative effects of chronic rapamycin treatment in AAV-mediated alpha-synuclein (a-syn) overexpression model of Parkinson’s disease (PD), designed to induce hippocampal…Evaluation of bedside tests of attention in delirium superimposed on Parkinson’s disease and dementia
Objective: To evaluate the ability of simple bedside tests for attention to detect delirium in those with and without underlying neurodegenerative diseases, including Parkinson’s disease…Single-Trajectory Multiple-Target Deep Brain Stimulation to treat Mobility and Cognition in Parkinson’s Disease: a Double-Blind, Randomized, Cross-Over Pilot Study
Objective: To assess the benefit of deep brain stimulation (DBS) to improve cognition in Parkinson’s Disease (PD). Background: Patients with advanced PD suffer from both…
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