Articles tagged "Dementia with Lewy bodies (DLB)"

MDS Virtual Congress 2021
AMP PD: Collaborating in the discovery of biomarkers to accelerate the development of therapies for Parkinson’s disease
C. Swanson-Fischer, E. Appelmans, D. Babcock, M. Bookman, D. Alonso, L. Kirsch, C. Wonders, J. Ward, S. Biswas, S. Dey, A. Singleton, H. Iwaki (North Bethesda, USA)
Objective: The Accelerating Medicines Partnership in Parkinson’s Disease (AMP PD; https://amp-pd.org) aims to identify and validate diagnostic, prognostic, and progression biomarkers for Parkinson’s Disease (PD).…
MDS Virtual Congress 2021
Non-Tremor Motor Dysfunction is Associated with AD Biomarkers in Lewy Body Dementias
I. Walker, S. Shaw, S. Vaishnavi, D. Wolk, N. Dahodwala, J. Morley, J. Duda, A. Chen-Plotkin, A. Siderowf, L. Shaw, E. Lee, J. Trojanowski, M. Grossman, D. Weintraub, D. Irwin (Philadelphia, USA)
Objective: To investigate the clinical influence of Alzheimer’s disease (AD) co-pathology on motor features in Lewy Body Dementia (LBD). Background: There is considerable heterogeneity of…
MDS Virtual Congress 2021
Analysis of the HLA locus in isolated REM sleep behavior disorder and Lewy body dementia
E. Yu, L. Krohn, J. Ruskey, F. Asayesh, S. Laurent, D. Spiegelman, Z. Shah, I. Arnulf, M. Hu, J. Montplaisir, JF. Gagnon, A. Desautels, Y. Dauvilliers, G. Gigli, M. Valente, F. Janes, A. Bernardini, B. Högl, A. Stefani, A. Ibrahim, K. Sonka, D. Kemlink, W. Oertel, A. Janzen, G. Plazzi, E. Antelmi, M. Figorilli, M. Puligheddu, B. Mollenhauer, C. Trenkwalder, F. Sixel-Döring, V. Cochen, C. Monaca, A. Heidbreder, L. Ferini-Strambi, F. Dijkstra, M. Viaene, B. Abril, B. Boeve, G. Rouleau, R. Postuma, S. Scholz, Z. Gan-Or (Montreal, Canada)
Objective: To examine genetic association of HLA alleles and amino acid for isolated REM sleep behavior disorder (iRBD) and Lewy body dementia (LBD). We compare…
MDS Virtual Congress 2021
CHARACTERIZATION OF LRP10 EXPRESSION IN LEWY BODY DISORDERS AND IPSC-DERIVED BRAIN CELLS
M. Grochowska, A. Carreras Mascaro, V. Boumeester, D. Natale, G. Breedveld, H. Geut, W. van Cappellen, A. Boon, A. Kievit, E. Sammler, P. Parchi, P. Cortelli, D. Alessi, W. V.D. Berg, V. Bonifati, W. Mandemakers (Rotterdam, Netherlands)
Objective: Our objective is to characterize endogenous low-density lipoprotein-related protein 10 (LRP10) expression in human induced pluripotent stem cell (iPSC)-derived brain cell types, post-mortem brain…
MDS Virtual Congress 2020
Predictors of the progression of dementia with Lewy bodies
A. Chimagomedova, O. Levin (Moscow, Russian Federation)
Objective: To define predictors of the progression of dementia with Lewy bodies (DLB). Background: Dementia with Lewy bodies is a progressive disabling neurodegenerative disease with…
MDS Virtual Congress 2020
Comparison of 123I-MIBG myocardial scintigraphy and 123I-FP-CIT SPECT between dementia with Lewy bodies and Parkinson’s disease
Y. Asahara, S. Miyagawa, M. Suzuki (Tokyo, Japan)
Objective: The objective of this study was to compare the nuclear medicine images of dementia with Lewy bodies (DLB) and Parkinson's disease (PD) patients and to extract findings…
MDS Virtual Congress 2020
Relationship Between a-syn RT-QuIC and a-syn Neuropathologic Burden in Dementia with Lewy Bodies
D. Coughlin, C. Orru, B. Groveman, A. Hiniker, R. Rissman, B. Caughey, D. Galasko (San Diego, CA, USA)
Objective: To determine if measures of alpha-synuclein (a-syn) real time quaking induced conversion (RT-QuIC) activity are related to a-syn neuropathologic burden in dementia with Lewy…
MDS Virtual Congress 2020
Confrontation Naming Deficit in Lewy Body Dementia Patients with Alzheimer’s Disease Co-Pathology
E. Howard, D. Irwin, K. Rascovsky, N. Nevler, S. Shellikeri, D. Mechanic-Hamilton, T. Tropea, A. Chen-Plotkin, A. Siderowf, D. Weintraub, L. Shaw, J. Trojanowski, M. Grossman, K. Cousins (Philadelphia, PA, USA)
Objective: To test the association between confrontation naming performance and Alzheimer’s disease (AD) co-pathology as defined by cerebrospinal fluid (CSF) biomarkers in Lewy body dementia…
MDS Virtual Congress 2020
Serum Neurofilament light chain levels and disability milestones in Lewy body diseases
A. Pilotto, A. Imarisio, F. Conforti, A. Lupini, G. Giannì, S. Gipponi, E. Cottini, A. Scalvini, S. Masciocchi, S. Nocivelli, R. Grasso, R. Turrone, B. Borroni, M. Rizzetti, L. Bonanni, M. Pizzi, A. Bellucci, E. Garraffa, H. Zetterberg, N. Ashton, A. Hye, A. Padovani (Brescia, Italy)
Objective: To evaluate the relationship between motor, cognitive and autonomic symptoms and serum Neurofilament light chain levels in Lewy bodies disorders, namely Parkinson' s disease…
MDS Virtual Congress 2020
A brain signature of prodromal Lewy body dementia
S. Rahayel, R. Postuma, J. Montplaisir, B. Mišić, C. Tremblay, C. Yao, M. Gaubert, J. Carrier, O. Monchi, F. Blanc, S. Chouinard, M. Panisset, A. Dagher, J.F Gagnon (Montreal, QC, Canada)
Objective: To investigate the presence of a brain signature able to predict the development of dementia in patients with idiopathic REM sleep behavior disorder (iRBD).…