Surface Modified Solid Lipid Nanoparticles for the targeted delivery to brain: Management of HIV-1 Associated Dementia
Objective: In this study, nifedipine loaded solid lipid nanoparticles (SLN) were developed for targeting drug into the central nervous system, the site of action of…A Florbetapir [F18] amyloid PET Imaging study in Parkinson’s disease Dementia (PDD): The influence of amyloid deposition on cognitive status and course of disease progression
Objective: To determine whether amyloid deposition, as assessed by PET imaging with the [18F]-Florbetapir, is related in patients with Parkinson Disease and Dementia (PDD) to…Motor and non-motor correlates of APOE-ε4 mediated cerebrospinal fluid concentrations of amino acids and monoamine metabolites in dementia with Lewy bodies compared with Alzheimer’s dementia and healthy controls
Objective: To study associations of cerebrospinal fluid (CSF) amino acids and monoamine metabolites with motor and non-motor features in dementia with Lewy bodies (DLB) compared…An atutopsy case of argyrophilic grain disease, clinically presenting with Parkinson dementia
Objective: We here reported argyrophilic grain disases (AGD) with clinical diagnosis of Parkinson dementia. Background: AGD is a four-repeat tauopathy and its accumulation (argyrophilic grain…Early gastrointestinal dysfunction is predictive of faster progression in Parkinson’s disease
Objective: To evaluate whether constipation at time of diagnosis has prognostic significance in terms of motor and cognitive progression in PD. Background: There is evidence…The relationship between family care giver number and progression speed of dementia
Objective: Study the fact delays dementia progression. Background: Alzheimer’s disease is unrestored yet now. Relieving the life upset of patient and postponing the disease progression…Serum insulin-like growth factor-1 levels in parkinsonism or dementia disorders
Objective: To investigate serum insulin growth factor-1 (IGF-1) levels in neurodegenerative disease and to correlate clinical parameters. Background: IGF-1 is highly expressed in the central…Nonlinearities in outcome-specific hazard of motor and nonmotor long-term complications of Parkinson’s disease
Objective: To estimate the specific hazard of motor and nonmotor milestones of Parkinson's disease (PD) progression in the long term. Background: Parkinson’s disease greatly varies…Angiotensin-converting enzyme inhibitors are neuroprotective regarding APOE-mediated motor and non-motor experiences for Alzheimer’s dementia but not for dementia with Lewy bodies
Objective: To assess whether angiotensin-converting enzyme (ACE) inhibitors modulate associations of biofluid concentrations and activity of ACE with motor and non-motor experiences in dementia with…A bayesian network approach for prediction of future dementia in Parkinson’s disease
Objective: To predict subsequent development of Parkinson’s dementia using parameters which can be easily obtained in a regular clinic visit using a machine learning approach.…
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