Longitudinal analysis of the relation of dopamine agonist use with impulse control disorders in Parkinson’s disease
Objective: To investigate the longitudinal relationship between dopaminergic therapies and impulse control disorders (ICD) in PD. Background: ICD are frequently associated with dopaminergic therapy, particularly dopamine…Impulsive-compulsive behaviors in patients with Parkinson’s disease and demographically-comparable group of healthy controls
Objective: To assess patients with Parkinson's disease (PwPD) impulsive-compulsive behaviors (ICBs) prevalence compared to healthy controls (HCs) group, to analyze PD clinical features, ICBs risk…Predicting incident impulse control disorder behaviour in Parkinson’s disease patients using a clinical-genetic model
Objective: Our aims were to estimate ICD heritability and to predict incident ICD behaviour by a candidate genetic multivariable panel in PD patients. Background: Impulse…EARLYSTIM: STN-DBS alleviates behavioural side effects of dopamine replacement therapy when compared to best medical treatment
Objective: To compare effects of STN-DBS and dopamine replacement therapy (DRT) on behaviour in PD in a 2 year follow-up study. Background: A large panel…Relationship between the MDS-UPDRS and quality of life in Parkinson’s disease: A large international multicenter study of 3206 patients (the QUALPD study)
Objective: To evaluate the relationship between the International Parkinson and Movement Disorder Society – Unified Parkinson's disease Rating Scale (MDS-UPDRS) and Quality of Life (QoL)…Higher doses of dopamine agonists, impulse control disorders and history of deep brain stimulation (DBS): Risk factors for dopamine agonists withdrawal syndrome (DAWS)?
Objective: To identify risk factors in the development of DAWS in patients with Parkinson's disease (PD). Background: DAWS is often a severe, stereotyped cluster of…Impulse control disorder associates with tyrosine hydroxylase 2 gene variants in Parkinson’s disease patients subject to dopaminergic therapy
Objective: The aim of this study was to identify novel genetic variants associated with Impulse control disorder (ICD) manifestation in PD patients subject to dopaminergic…Successful DBS: Doctors happy, patients not – Why?
Objective: Deep brain stimulation (DBS) in Parkinson's disease (PD) has been proven successful; however, not in all. Background: We report on 5 PD patients who…Effect of STN-DBS on impulse control disorder and affective behavioral complications of Parkinson’s disease: A 1-year longitudinal study
Objective: In this 1-year prospective study, we evaluated the effect of bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN) on neuropsychiatric complications of…Dopamine dysregulation syndrome /DDS/ in LCIG infusion: Successful treatment without interrupting the pump therapy
Objective: Here we report the case of a 49-year-old man with a 19 years history of PD presenting DDS while he was on LCIG therapy.…