Dual-site rTMS for Essential Tremor
Objective: To evaluate the safety and therapeutic potential of dual-site repetitive transcranial magnetic stimulation (rTMS) targeting the supplementary motor area (SMA) and cerebellum in medication-refractory…Remaining unmet needs in Essential Tremor and Parkinson’s Disease: European Neurologists’ Assessments of Pharmacologic Response and Advanced Therapy Use
Objective: To investigate neurologists’ perceptions of treatment effectiveness and criteria for selecting patients for advanced therapies in essential tremor (ET) and Parkinson’s disease (PD). Background:…Stimulation-Induced Laryngospasm During Awake Ventral Intermediate Nucleus Deep Brain Stimulation for Essential Tremor
Objective: To report a rare case of acute laryngospasm during intraoperative stimulation in VIM-DBS surgery. Background: Deep brain stimulation (DBS) of the ventral intermediate nucleus…Bilateral MRgFUS thalamotomy in essential tremor: a prospective case series using probabilistic tractography
Objective: To evaluate the efficacy and safety of staged bilateral MRgFUS thalamotomy guided by probabilistic tractography. Background: Magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy is an…Prospective International Registry Evaluating Real-World Clinical and Quality-of-Life Outcomes of Directional Deep Brain Stimulation in Essential Tremor
Objective: To assess real-world clinical effectiveness and patient-reported outcomes associated with a multiple independent constant current (MICC) directional deep brain stimulation (DBS) system in individuals…Quantitative Changes in Speech After Focused Ultrasound Thalamotomy in Parkinson’s Disease and Essential Tremor
Objective: To compare speech performance following unilateral MR-guided focused ultrasound (MRgFUS) targeting the ventral intermediate nucleus (VIM) of the thalamus in Parkinson’s disease (PD) and…Association study of genetic variants with Essential Tremor
Objective: Using a large case-control study to examine the association of rs17590046 (PPARGC1A) and rs28562175 (LOC) with ET in an Asian cohort. Background: Essential tremor…Reduced Motor Unit Discharge Variability of Wrist Muscles 24 Hours After Closed-Loop Electrical Stimulation in Essential Tremor
Objective: To investigate the acute and sustained effects of two peripheral electrical stimulation strategies on motor unit activity of wrist flexors and extensors in individuals…Clinical Features of Patients with an Essential Tremor–to–Parkinson’s Disease Diagnostic Trajectory
Objective: To characterize the clinical phenotype and disease course of patients with an ET-to-PD diagnostic trajectory in a tertiary-care setting. Background: The longitudinal clinical features…Quantitative Changes in Speech After Unilateral and Bilateral VIM MRgFUS Thalamotomy in Essential Tremor
Objective: To assess speech outcomes in patients with essential tremor (ET) following unilateral and bilateral MR-guided focused ultrasound (MRgFUS) thalamotomy targeting the ventral intermediate nucleus…
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