Diagnostic Test Utilization and Timing in a Multidisciplinary Gastrointestinal Symptom Clinic: Insights from the Parkinson’s Research and Integrated Support Model (PRISM) Clinic
Objective: This study evaluates the diagnostic yield of an algorithm-based approach implemented in the Parkinson’s Research and Integrated Support Model (PRISM) clinic [1]. Background: Gastrointestinal…Evaluating the Relationship between Depression and Other Non-Motor Symptoms in Parkinson’s Disease
Objective: Investigate the correlation between depression and other non-motor symptoms, such as cognitive impairment and gastrointestinal (GI) dysfunction in Parkinson’s disease (PD). Background: In addition…Regional Homogeneity in the Visual Network Mediates between Microbiota and Cognition in Parkinson’s Disease
Objective: We study the role of spontaneous brain activity in the cross-talk between gut microbiota and cognition in PD. Background: Gut dysbiosis is a prevalent…The Nature of autonomic dysfunction and its relationship with motor symptoms in Drug-Naive Parkinson’s Disease Patients: Korean Cohort Data
Objective: We aimed to characterize the domain-specific distribution of autonomic symptoms in newly diagnosed, drug-naive PD and to investigate whether distinct autonomic patterns are associated…Choreoathetosis revealing vitamin B12 deficiency : an unusual manifestation of subacute combined degeneration
Objective: To describe an uncommon case of choreoathetosis secondary to vitamin B12 deficiency, highlighting the importance of recognizing atypical movement disorders linked to metabolic causes.…The Clinical and Biological effects of a Whole Foods and Plant-Based Dietary Intervention in Parkinson’s Disease
Objective: The Plants for Parkinson trial aims to investigate whether prolonged adherence to a plant-based and whole foods-derived dietary pattern can alleviate motor- and gastrointestinal…The enteric footprint of de novo parkinson’s disease cohort: constipation, inflammation, and nulisa biomarker profiling.
Objective: This study aimed to analyze constipation symptoms and blood, CSF and fecal biomarkers, including a High-plex Profiling of Inflammatory Proteins (NULISA) in a de novo PD cohort. Background: Parkinson’s disease…Association Between Esophageal Motility and Gait in Parkinson’s Disease: Possible Differential Mechanisms by Esophageal Region
Objective: To investigate the association between esophageal motility and quantitative gait parameters in patients with Parkinson's disease (PD). Background: PD is the second most common…The Unholy Marriage Between Ogilvie Syndrome and Parkinson’s Disease
Objective: To demonstrate the dynamic interplay between advanced Parkinson’s disease (PD)–related colonic dysmotility and acute colonic pseudo-obstruction (ACPO; Ogilvie syndrome) and to highlight practical red…NIH Multicenter Consortium for Gut-Brain Communication in Parkinson’s Disease: The Master Protocol and Timeline
Objective: To describe the master protocol and timeline for the multicenter Gut-Brain Communication in Parkinson’s Disease Consortium (GBPDC), funded by NIDDK/NIH (UO1) from 2024 to…
