Contribution of external globus pallidus to motor deficits of Parkinson’s disease: optogenetic studies in murine model
Objective: The present study explored whether altered activity of external globus pallidus (GPe) neurons contributes to the development of motor deficits of Parkinson’s disease (PD).…Bilateral Globus Pallidus interna Deep Brain Stimulation for the treatment of chorea-acanthocytosis: A case report from South Africa
Objective: We report on the efficacy of bilateral Globus pallidus interna deep brain stimulation as a treatment for Chorea-acanthocytosis (ChAc). Background: ChAc is an autosomal…A systematic review to compare the effect of bilateral deep brain stimulation (STN versus GPI) on gait and balance in Parkinson’s disease
Objective: To compare the effect of bilateral sub-thalamic nucleus (STN) deep brain stimulation (DBS) and Globus pallidus interna (GPI) DBS on gait and postural stability in Parkinson’s…The role of intraoperative electrophysiological monitoring in implanting globus pallidus internus electrodes in patients with dystonia
Objective: The first aim was to compare the preplanned GPi electrode neuroradiological trajectory with the final trajectory selected after electrophysiological monitoring. The second aim was…Structural connectivity affecting freezing of gait after globus pallidus internus deep brain stimulation in Parkinson’s disease
Objective: We aim to investigate how structural connectivity of the brain affects gait freezing after globus pallidus internus (GPi) deep brain stimulation (DBS). Background: Freezing…Unilateral Subthalamic Versus Unilateral Pallidal Stimulation in Parkinson’s Disease: A Randomized Double-Blind Crossover Study
Objective: To compare the acute effects of deep brain stimulation (DBS) of unilateral subthalamic nucleus (STN) and unilateral globus pallidus interna (GPi) on motor function…Pallidal deep brain stimulation entrains finely tuned gamma oscillations in motor cortex
Objective: Determine whether therapeutic pallidal deep brain stimulation can entrain finely tuned gamma oscillations in the motor cortex. Background: In Parkinson’s disease (PD), finely tuned…Movement vigor is differentially encoded in motor cortex and globus pallidus in Parkinson disease
Objective: To test the hypothesis that pallidocortical local field potential (LFP) beta oscillations encode movement vigor. Background: Recent work suggests the motor basal ganglia adjusts…Retrospective Review of Globus Pallidus Deep Brain Stimulation Electrode Contact Locations and Clinical Outcomes in Parkinson’s Disease
Objective: To evaluate the location of therapeutic electrode contacts and correlate those with the clinical outcomes of deep brain stimulation (DBS) of the globus pallidus…The role of genetics in patient selection and outcomes of deep brain stimulation in Parkinson’s disease
Objective: Determine the role of genetic factors in selecting candidates for, and evaluating outcomes of, deep-brain stimulation (DBS) within the framework of the multi-national Genetic…
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