Elevated nigral iron is associated with low plasma serotonin in Parkinson’s disease
Objective: The objective of this work was to determine whether plasma serotonin levels in Parkinson’s disease (PD) are related to iron levels in the brain,…Visualization of Nigrosome 1 at 3T MRI and 18F-DOPA PET for the diagnosis of Parkinson´s disease
Objective: To determine and compare the utility of Nigrosome 1 at 3T MRI and 18F-DOPA PET for the diagnosis of Parkinson´s disease. Background: Differential diagnosis…The interaction between iron metabolism and inflammation in Parkinson´s disease: an in vivo and post mortem study
Objective: To assess the relationship iron and inflammatory markers in an in vivo and post mortem study of Parkinson´s disease subjects. Background: Although neuroinflammation and…Restless legs syndrome in a patient with hereditary hemochromatosis
Objective: We present a case with two disorders, hereditary hemochromatosis (HH) and Restless Legs Syndrome (RLS), each related to the two ends of the spectrum…Caudal posterior substantia nigra iron increases longitudinally in Parkinson’s disease
Objective: To investigate spatial patterns and temporal evolution of substantia nigra (SN) iron accumulation in Parkinson’s disease (PD) using quantitative susceptibility mapping (QSM), an indirect…In vivo increased striatal iron deposition in Parkinson’s Disease Dementia and Dementia with Lewy Body
Objective: To evaluate iron deposition with susceptibility weighted imaging (SWI) MRI in the basal ganglia of patients affected by Parkinson’s Disease Dementia (PDD) and Dementia…Quantification of regional iron content with Susceptibility Weighted Imaging in Huntington Disease Expansion Gene Carriers
Objective: To assess brain iron content measured with SWI-MRI in HD gene expansion carriers (HDGECs). Background: Huntington’s Disease (HD) results in extensive neuronal cell loss,…Safety of Iron Chelation in Patients with Brain Iron Overload
Objective: To assess the safety of iron chelation in the treatment of regional brain iron overload. Background: Excess brain iron is evident in neurodegenerative diseases…Iron Supplementation for the Treatment of Restless Legs Syndrome – A Systematic Review and Meta-Analysis
Objective: To gather the evidence for the efficacy and safety of iron supplementation for restless legs syndrome (RLS). Background: Iron supplementation is used for the…Nigral Iron Load as Diagnostic Parameter in Parkinson’s Disease
Objective: The aim of our study was to determine the diagnostic value of nigral iron depositions in PD, measured by iron specific MRI-techniques. Background: Nigral…