Availability of levodopa and clinicopathological features of patients with multiple system atrophy
Objective: To investigate the availability of levodopa for pathologically confirmed multiple system atrophy (MSA) patients and determine the clinicopathological features of levodopa responders with MSA.…Continuous levodopa- carbidopa gel recovers motor cortex plasticity in advanced Parkinson’s disease
Objective: The objective of this study was to investigate if continuous infusion of levodopa- carbidopa gel (LCIG) improves motor complications of Parkinson's disease (PD) and…Opposing effects of levodopa on basal ganglia activity in Parkinson’s disease during motion and rest
Objective: To explore the pattern of activation within the motor network during the movement and resting phases of the tapping task in Parkinson’s disease (PD)…Gastrointestinal symptoms as a risk factor for the appearance of motor fluctuations in patients with advanced Parkinson disease
Objective: Gastrointestinal alterations in patients with Parkinson`s Disease (EP) provoke alterations in the absorption of levodopa that facilitates the development of motor fluctuations. Study the…Impact of repeated oral administration of Opicapone on the plasma pharmacokinetics of levodopa
Objective: To examine the inhibitory effect of COMT on the plasma pharmacokinetics of levodopa resulting from repeated, once daily, oral administration of an Opicapone (OPC)…The effect of ADORA2A gene polymorphism on the dyskinesia of Parkinson’s Disease
Objective: To investigate the relationship of levodopa-induced dyskinesia with ADORA2A gene polymorphisms in PD patients. Background: With the progression of the disease, motor complications and…Memory enhancing effect of Combined Alcoholic Extract of Cedrus deodara Loud. and Vitex Nirgundi in scopolamine-induced cognitive impairment in mice
Objective: Epidemiological studies of Indian population reveal that dementia is largely a hidden problem in India. Ayurveda claims several plants are beneficial in cognitive disorders.…Effects of levodopa on prosaccade performance and visual target eccentricity
Objective: To investigate whether the effect of levodopa on saccade is the same to visual targets of small and large eccentricities in Parkinson’s disease (PD)…Preserved white matter microstructure in Parkinson’s disease patients with levodopa-induced dyskinesia: Evaluation by neurite orientation dispersion and density imaging (NODDI)
Objective: Brain microstructure alteration using MRI in Parkinson's disease (PD) have not been well studied. We analysis the white matter alterations in Parkinson’s disease with…Long-Duration Response to Levodopa in advanced Parkinson’s Disease: Relevance for RCT on Disease-Modifying therapies
Objective: (1) To investigate the natural history of Parkinson’s disease (PD) in a cohort of newly diagnosed patients and (2) the response to acute levodopa…
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