Neuroprotective efficacy of EDTA against manganese neurotoxicity: Implications for modulating Parkinsonian syndromes
Objective: This study investigates the neuroprotective potential of ethylenediaminetetraacetic acid (EDTA) in reducing the neurotoxic effects of manganese (Mn), focusing on both motor and non-motor…Ataxia, the initial symptom in a patient with Huntington’s Disease and Acquired (non-Wilsonian) Hepatocerebral Degeneration
Objective: To describe a patient with Huntington disease and acquired (non-Wilsonian) hepatocerebral degeneration (AHD) presenting with ataxia. Background: AHD is a neurological disorder that occurs…Manganese-induced Parkinsonism Vs Rotenone-induced Parkinsonism: Animal Life Matters!
Objective: To evaluate the Parkinsonism mimicking potential of MnCl2 in an experimental rat model.To compare the destructive effect of MnCl2 with rotenone by performing behavioral,…SLC39A8-CDG with manganese deficiency in an adult individual: a case report
Objective: To report the case of an adult male with SLC39A8-CDG and evaluate the effects of manganese supplementation on clinical evolution of the patient. Background:…A forgotten cause of ocular motor apraxia
Objective: To report an example of the rare association between acquired hepatocerebral degeneration (AHD) and ocular motor apraxia (OA), and discuss its relevance for topical…Therapeutic potential of luteolin in manganese induced Parkinson’s disease: Targeting neuroinflammation and oxidative stress.
Objective: To investigate the neurodegenerative facets of Manganese (Mn) in rat model in rat model of Parkinson's disease.To study the neuroprotective effect of luteolin in…Adults with slowly progressive dystonia-parkinsonism secondary to manganese accumulation
Objective: To expand the clinical spectrum of manganese-induced neurodegeneration. Background: Neurodegeneration induced by manganese accumulation is a potentially treatable condition and therefore should not be…Clinical profile and treatment outcomes of inherited hypermanganesemia among 27 Indian children: A retrospective multi-centric study
Objective: To describe clinical, laboratory features and treatment outcomes among children with IH-Mn Background: Inherited hypermanganesemia (IH-Mn) is a recently described neurogenetic condition caused by mutations…Inhibition of mitochondrial complexes induces unique transcriptomic and epigenetic profiles: implications to neurodegeneration induced movement disorders
Objective: To compare the neurotoxicological hallmarks induced by inhibitors of mitochondrial complex I (CI- 1- methyl-4- phenylpyridinium; MPP+), complex II (CII- 3- nitropropionic acid; 3-…Toxin-induced Parkinsonism: A report of two patients
Objective: To highlight the presentation of parkinsonism caused by acute and chronic exposure to carbon monoxide(CO). Background: Toxin-induced parkinsonism is not uncommon. One of the…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.