The Cleveland Clinic-Virtual Home Environment (CC-VHE): A Reliable Way to Trigger Freezing of Gait in Parkinson’s disease
Objective: To describe the development, safety, and efficacy of the Cleveland Clinic-Virtual Home Environment (CC-VHE) in provoking freezing of gait (FOG) in Parkinson’s disease (PD).…A personalized gait signature assay in Parkinson’s disease
Objective: To establish a personalized gait signature assay to inform on progression, phenotype and effects of intervention of gait abnormalities in PD. Background: Gait signatures…Health Disparity in Rural Southern California
Objective: To analyze the demographic and clinical characteristics of hispanic patients with Parkinson's disease in rural southern California Background: Parkinson’s disease (PD) is the second…The Role of Knowledgeable Informants in the Early Detection of Parkinson’s Disease
Objective: To investigate the reporting of changes observed by Knowledgeable Informants (KIs) and people with Parkinson’s disease (PwPD) prior to a Parkinson’s disease (PD) diagnosis.…Parkinson’s Disease: Increased Presence of Neuropsychiatric Symptoms and Non-Motor Issues Drive Higher Medication Use and Costs
Objective: To compare neuropsychiatric disorders (NPsy), other non-motor symptoms (NMS), and associated medication use and costs in individuals with advanced Parkinson’s Disease (aPD) with those…The influence of Caffeine intake on Type 2 Diabetes Mellitus mediated risk of Parkinson’s Disease.
Objective: The objectives are to investigate if a diagnosis of Type 2 Diabetes Mellitus (T2DM) is associated with increased risk of developing Parkinson's Disease (PD)…Deferiprone improves striatal dopamine by reducing neuroinflammation and oxidative stress in MPTP-induced mice model of Parkinson’s disease
Objective: This study aimed to investigate the effect of deferiprone on the striatal DA, oxidative stress and neuroinflammation markers as well as motor deficits in…Rescuing alpha-synuclein toxicity through neuron-specific enhancement of autophagy
Objective: In the present study, we aim to counteract regulatory and transcriptional modifiers of autophagy to enhance neuroprotective proteostasis and rescue alpha-synuclein (asyn) toxicity in…Mathematical and Computational Modeling Prototype to Understand the Evolution of Parkinson’s disease using Four Differential Equations
Objective: Apply four differential equations to generate projections considering the effect of dopamine on Parkinson’s disease progression, leading to the development of an initial prototype…Comparison of MIBG Uptake in the Major Salivary Glands Between Rapid Eye Movement Sleep Behavior Disorder and Parkinson’s Disease
Objective: This study aimed to evaluate 123I-metaiodobenzylguanidine (MIBG) uptake in the major salivary glands (MSG) in patients with rapid eye movement sleep behavior disorder (RBD)…
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