TMS-EEG Provides Objective Neurophysiological Measures of Motor Fluctuations in Parkinson’s Disease
Objective: To assess the correlates TMS evoked potentials (TEPs) measurements changes representing interhemispheric transmission to the change in motor symptoms in 'off' versus 'on' states.…Combining Pharmaceutical and Digital Treatment Approaches in Parkinson’s Disease Modulates of the Limbic System, Supporting Emotional Regulation and Motivated Behaviors
Objective: Following the combination of standard levodopa treatment with a digital intervention in Parkinson's disease (PD), we assessed the associations between neuroplasticity within the limbic…Gray Matter Microstructural Integrity in Relation to Frontostriatal and Posterior Cortical Cognitive Performance in Parkinson’s Disease
Objective: Explore relationships of frontostriatal (FS) and posterior cortical (PC) cognitive performance with gray matter (GM) microstructural integrity in Parkinson’s disease (PD). Background: The dual…LRRK2 Polymorphisms and Associations with Parkinson’s Disease in Participants of East Asian, Southeast Asian, and European Descent
Objective: To investigate the prevalence of LRRK2 polymorphisms, R1628P and G2019S, and their association with Parkinson’s Disease (PD) in cohorts of East Asian (EA), Southeast…Rare Variant Analysis of Sphingolipid-related Genes in Large Chinese Parkinson’ s Disease Cohorts
Objective: This study investigated the link between rare variants in sphingolipid-related genes and Parkinson’s disease (PD) in a Chinese mainland population. Background: Recently, growing evidence…Longitudinal Analysis of Disease Progression in GBA-Associated Early-Onset Parkinson’s Disease
Objective: This study aims to investigate the longitudinal disease progression of early-onset Parkinson’s disease (EOPD) in carriers of GBA mutations compared to genetically undefined EOPD…Monogenic Parkinson’s Disease patients in Central Europe within the CEGEMOD consortium
Objective: To report the genetic results of genotyping and whole-exome sequencing (WES) data of patients with Parkinson’s disease (PD) from the Central European countries of…Genetic risk modifiers for GBA1 carriers in Parkinson’s disease: from the Global Parkinson’s Genetics Program
Objective: To identify potential genetic risk modifiers for GBA1 variant carriers across genetically determined European ancestries (European, Ashkenazi Jewish, Finnish, and Icelandic) using data from…Digital Health Technology Demonstrates Efficacy of Algorithmic DBS Programming
Objective: To test the feasibility and performance of algorithmic image-guided programming for deep brain stimulation (DBS) using a digital health technology, Quantitative Digitography (QDG), as…Deep Brain Stimulation (DBS) Placement in a Patient with Parkinson’s disease (PD) and Polyostotic Fibrous Dysplasia (PFD)
Objective: To describe a patient who has PD and a history of PFD implanted with DBS. Background: PD is the second most common neurogenerative disorder…
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