Comparative Safety of Different Routes of Apomorphine Administration in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: To assess the safety profiles of inhaled, sublingual, and subcutaneous apomorphine in patients with Parkinson’s disease (PD). Background: Apomorphine is a direct-acting D1/D2 agonist…Glucagon Like Peptide-1 (GLP-1) Receptor Agonists for Parkinson’s Disease: An Updated Systematic Review and Meta-Analysis
Objective: To evaluate the efficacy and safety of GLP-1 receptor agonists in Parkinson's disease (PD) by adding new 2025 randomized controlled trial (RCT) data, and…Synchronized High Frequency Neural Oscillations as a Biomarker for Differentiating the Internal from the External Segment of the Globus Pallidus in Parkinson’s Disease
Objective: To assess whether using high frequency oscillations (HFO; 150-350 Hz) or beta band oscillations (13-30 Hz) can objectively differentiate the external from the internal…Utilization of Phosphorylated Alpha-Synuclein Skin Biopsy Testing in a Movement Disorders Center
Objective: To describe the utilization patterns of skin biopsy for phosphorylated alpha-synuclein (P-syn) aggregation obtained from three sites (posterior cervical, distal thigh, distal leg) and…Three Biopsies Optimizes Test Performance for the Detection of Cutaneous Phosphorylated Alpha-Synuclein
Objective: To review two independent data sets to define the test performance of skin biopsies for the detection of P-SYN and peripheral nerve degeneration in…Eye tracking identifies biomarkers predicting Parkinson’s disease before motor symptom onset
Objective: To investigate eye movement changes as an early motor biomarker of Parkinson’s disease (PD) in patients with REM sleep behavior disorder (RBD). Background: RBD…Daily Activity Analysis of Parkinson’s Disease Using Machine Learning with 3D Poses
Objective: This study aims to find a digital behavioral marker Parkinson’s disease (PD) in activities of daily living via machine learning (ML) analysis of 3D…Tracking Cognitive Decline and Understanding Study Dropout in PD-GBA
Objective: Analyze which cognitive functions are affected in PD_GBA+, and which factors are linked to dropout risk. Background: People with Parkinson's disease (PD) who carry…The Cultural Validation of the Montreal Cognitive Assessment in Bangladeshi Adults with Parkinson’s Disease in East London
Objective: This study investigated the cultural validity of the Montreal Cognitive Assessment (MoCA) in Bangladeshi adults with Parkinson’s disease in East London using the validated…Theta and Beta Oscillations Track Happiness and Surprise in the Subthalamic Nucleus After Reward Outcome
Objective: To identify subcortical neural biomarkers of happiness and reward evaluation through sensing-enabled deep brain stimulation (DBS) in people with Parkinson’s Disease (PwPD). Background: Integrating…
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