Impaired Mitophagy and Mitochondrial-energetics in Parkinson’s disease: A Novel Therapeutic Strategy of Re-tasking Felodipine
Objective: This study aimed to validate impairment of mitochondrial energetics and mitophagy in PD and the action of felodipine in restoring altered Mitochondria-lysosome (Mito-Lyso) homeostasis.…Agreement between swallow tail sign asymmetry and clinical laterality in Parkinson’s disease
Objective: Our goal was to evaluate the concordance between asymmetry in nigral hyperintensity detected with 3T MRI and clinical symptomatology. Background: A promising MRI marker…Evaluation of small extracellular vesicles derived miRNA as biomarkers for Parkinson’s disease: comparison with plasma miRNA
Objective: To identify differentially expressed small extracellular vesicles (sEV) derived miRNAs in Parkinson’s disease using small RNA-sequencing and to evaluate their potential as biomarker targets.…Unsupervised multimodal digital assessment of fatigue and sleep disorders in Parkinson’s disease: the IDEA-FAST study
Objective: To evaluate fatigue and sleep disorders in unsupervised conditions in neurodegenerative and autoimmune conditions using a combination of mobility, autonomic and sleep digital home…Classification and genotype-phenotype relationships of GBA1 variants and Parkinson’s disease: MDSGene Systematic Review
Objective: To provide a comprehensive and systematic literature review of variants in the glucocerebrosidase 1 gene (GBA1) linked to Parkinson’s disease (PD). Background: Approximately 10% of patients with PD…Parkinson’s Disease Hospital Optimization Project
Objective: To describe The Parkinson’s Disease Hospital Optimization Project (PD-HOP) that we established to optimize inpatient care and improve the hospital experience and outcomes for…Anodal Transcranial Direct Current Stimulation (tDCS) on sensorimotor cortex in patients with early-onset Parkinson’s Disease: a Pilot Study.
Objective: To evaluate the clinical effects of anodal Transcranial Direct Current Stimulation (tDCS) application on sensorimotor cortex in a group of early-onset Parkinson’s Disease patients.…Ethical considerations in person-centered Parkinson’s disease care: a cross-national comparison of patients’ perspectives
Objective: To identify which ethical requirements are placed by people with Parkinson’s disease (PwPDs) and their care partners on person-centered care. Background: To improve the…Predictors of death in Parkinson’s disease
Objective: To investigate how clinical, motor and behavioural characteristics impact on Parkinson mortality in a cohort from a tertiary movement disorders specialty center . Background:…Effects of a rhythmic auditory stimulation-enhanced walking program on Veterans with Parkinson’s disease with and without subthalamic nucleus deep brain stimulation.
Objective: Describe outcomes from a 12-week home-based rhythmic auditory stimulation (RAS)-enhanced walking program completed by Veterans with Parkinson’s disease (PD); 1 with subthalamic nucleus deep brain stimulation…
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