Characteristics of daily exercise patterns in various stages of Parkinson’s disease
Objective: To investigate the patterns of exercise in the daily lives of mild to severe PD patients. Background: Despite the reported clinical impact of exercise…Perampanel inhibits α-synuclein transmission in Parkinson’s disease models
Objective: To examine the effect of perampanel, an antiepileptic drug, on α-synuclein transmission in cultured cells and mouse models of Parkinson’s disease. Background: The intercellular transmission of pathogenic proteins…Effects of levodopa on cognitive functions in Parkinson’s disease
Objective: To assess the dynamics of cognitive functions (CF) under the influence of levodopa in PD patients Background: Our research is devoted to an urgent problem-the…The Functional Impact of REM Sleep Behavior Disorder in Parkinson’s Disease with Mild Cognitive Impairment
Objective: This study examines whether severity and the functional impact of cognitive decline in Parkinson’s disease mild cognitive impairment (PD MCI) participants differ between those…Parkin Mutation and Deep Brain Stimulation
Objective: To investigate the clinical features of Parkin mutated patients who undergone subthalamic brain stimulation (DBS group) and pharmalogically treated only (Non-DBS group). Background: The…HYPERSEXUAL DISORDER IN GBA-ASSOCIATED PARKINSON’S DISEASE: CASE REPORT
Objective: To describe a patient with PD and hypersexual disorder carrying a GBA variant. Background: Compulsive sexual behavior occurs in 4% of patients with Parkinson’s…The MJFF Global Genetic Parkinson’s Disease Research Resource
Objective: To establish a comprehensive research and clinical trial-ready resource of centers working with individuals with monogenic Parkinson’s Disease (PD). Background: As gene-targeted therapies are…The gut microbiome in Parkinson’s disease: longitudinal insights into disease progression and the use of device-assisted therapies.
Objective: We investigated the temporal stability of gut microbiome (GM) profiles from Parkinson’s disease (PD) patients initiating device-assisted therapies (DAT) and in a separate cohort…Neurogenetic Traits Outline Vulnerability to Cortical Disruption in Parkinson’s Disease
Objective: In this study, we characterized the brain topological intersection between propagating connectivity networks in healthy controls (HC) and Parkinson’s disease (PD) participants and gene…Dynamic functional connectivity changes in Parkinson’s disease patients with REM sleep behavior disorder
Objective: Our aim was to explore dynamic network connection changes in PD patients with RBD. Background: Rapid eye movement (REM) sleep behavior disorder (RBD) is…
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