PD GENEration Clinical Phase: Genetic Diagnostic Yield and Clinical Characteristics
Objective: To assess the frequency of reportable variants in major genes associated with Parkinson’s disease (PD) and identify clinical predictors of positive genetic test results.…Deep learning to distinguish Parkinson’s from controls in video, without human-defined measures
Objective: We aimed to apply a deep learning neural network directly to video of finger tapping, without human-defined measures or features, for a computer to…Characteristics and validity of technologies analyzing voice features to assess symptoms – a review
Objective: Our goal was to review the current literature aiming to (i) list, (ii) compare and (iii) classify voice-based technologies that objectively measure the presence…Prevalence of Parkinson’s disease and Atypical Parkinsonisms in Colombia: Data from the national health registry 2016-2021
Objective: To estimate prevalence of Parkinson’s Disease (PD) and Atypical Parkinsonisms and characterise the diagnosed population in a country with a development economy Background: The…Validation of a patient-reported functional mobility composite score (FMCS) in people with typical Parkinson’s disease
Objective: To investigate the convergent and discriminative validity of a patient-reported FMCS in people with typical PD (PwP). Background: Although a patient-reported instrument is less…Cognitive and Motor aspects of a Brazilian population with Parkinson´s disease and Impulse Control Disorders and/or Related Behaviors – an observational study.
Objective: We analysed if Impulse Control Disorders (ICDs) and/or Related Behaviors (RBs) were associated with levodopa-induced dyskinesia (LIDs) in Brazilian patients with Parkinson´s disease (PD)…Multimodal MRI assessment of the substantia nigra in premotor and motor stages of parkinsonism
Objective: To investigate substantia nigra (SN) MRI abnormalities through Neuromelanin (NM) and diffusion MRI (dMRI) with Neurite Orientation Dispersion and Density Index (NODDI) in the…Assessment of novel diffusion MRI metrics of cortical microstructure in the genetic continuum of Parkinson’s disease
Objective: To investigate novel cortical diffusivity metrics in Parkinson’s disease (PD), including both prodromal and established genetic PD, alongside sporadic PD and healthy controls (HC).…Identifying meaningful symptoms and impacts of disease for patients with early Parkinson’s disease
Objective: To explore meaningful symptoms and impacts of disease on daily living in individuals with early-stage Parkinson’s disease (PD). Background: Critical Path for Parkinson’s (CPP)…Gut dysbiosis in patients with dementia with Lewy bodies
Objective: To identify intestinal bacteria that are changed in DLB alone or in both DLB and cognitive decline in Parkinson’s disease (PD). Background: Gut microbiota…
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